Basal insulin treatment is indispensable for patients with type 1 diabetes and often required
by many with type 2 diabetes. Incremental advances lengthening the duration of action of …

Stackelberg evolutionary game (SEG) theory combines classical and evolutionary game
theory to frame interactions between a rational leader and evolving followers. In some of …

Importance Optimizing insulin therapy for patients with type 2 diabetes can be challenging
given the need for frequent dose adjustments. Most patients receive suboptimal doses and …

Background Short-term (2 weeks to 3 months) insulin intensive therapy using continuous
subcutaneous insulin infusion (CSII) can improve islet beta cell function and prolong …

Introduction Insulin treatment is fundamental to diabetes management. Basal insulin therapy
reduces intraday glycemic fluctuations upon reaching a steady state. Besides better blood …

Background: Real-world studies of people with type 2 diabetes (T2D) have shown
insufficient dose adjustment during basal insulin titration in clinical practice leading to …

Abstract Background Insulin Icodec is a novel basal insulin analog with once-weekly
subcutaneous administration. We aim to estimate the efficacy and safety of insulin icodec …

Cardiovascular diseases (CVDs) are the leading cause of death globally as well as the
leading cause of mortality and morbidity in type 2 diabetes (T2D) patients. Results from large …

Introduction Insulin resistance in muscle can originate from a sedentary lifestyle,
hypercaloric diets, or exposure to endocrine-disrupting pollutants such as arsenic. In …

Aim To evaluate gastric emptying (GE) and the glycaemic response to a 75‐g oral glucose
load in newly diagnosed, treatment‐naïve Han Chinese with type 2 diabetes (T2D) before …