Endoplasmic reticulum stress mediates nitric oxide-induced chondrocyte apoptosis
K Takada, J Hirose, S Yamabe… - Biomedical …, 2013 - spandidos-publications.com
Nitric oxide (NO) is one of the most important mediators of chondrocyte apoptosis, which is a
notable feature of cartilage degeneration. While apoptosis of chondrocytes is induced by …
notable feature of cartilage degeneration. While apoptosis of chondrocytes is induced by …
Over-expression of Bcl-2 against Pteris semipinnata L-induced apoptosis of human colon cancer cells via a NF-kappa B—related pathway
Abstract Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid (5F), an antitumor component, is a
chemical compound isolated from Pteris semipinnata L (PsL), a Chinese traditional herb. We …
chemical compound isolated from Pteris semipinnata L (PsL), a Chinese traditional herb. We …
Xiangshao Granules reduce the aggressive behavior and hippocampal injury of premenstrual irritability in rats by regulating JIK/JNK/p38 signal pathway
S Li, X Mu, S Ma, X Li, J Gao, X Liu, H Wang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance As a typical prescription for soothing the liver, Xiangshao
granule has a good effect on the symptoms of irritability and anxiety. Clinical evidence …
granule has a good effect on the symptoms of irritability and anxiety. Clinical evidence …
Apoptosis and autophagy in the pathogenesis of osteoarthritis
P Castrogiovanni, S Ravalli… - Journal of Investigative …, 2020 - Taylor & Francis
Osteoarthritis (OA) is a degenerative disease in which a low-grade inflammation in cartilage
and synovium occurs, causing a deterioration of cartilage and the consequent joint disability …
and synovium occurs, causing a deterioration of cartilage and the consequent joint disability …
Dual effect of the novel peptide antagonist K‐14585 on proteinase‐activated receptor‐2‐mediated signalling
FG Goh, PY Ng, M Nilsson, T Kanke… - British journal of …, 2009 - Wiley Online Library
Background and purpose: Here we have examined the effects of the novel peptide
antagonist N‐[1‐(2, 6‐dichlorophenyl) methyl]‐3‐(1‐pyrrolidinylmethyl)‐1H‐indol‐5‐yl] …
antagonist N‐[1‐(2, 6‐dichlorophenyl) methyl]‐3‐(1‐pyrrolidinylmethyl)‐1H‐indol‐5‐yl] …
[HTML][HTML] Resveratrol inhibits nitric oxide-induced apoptosis via the NF-kappa B pathway in rabbit articular chondrocytes
Abstract Resveratrol (trans-3, 4'-trihydroxystillbene), a naturally occurring polyphenolic
antioxidant found in grapes and red wine, elicits diverse biochemical responses and …
antioxidant found in grapes and red wine, elicits diverse biochemical responses and …
Induction of apoptosis by the licochalcone E in endothelial cells via modulation of NF-κB and Bcl-2 Family
HJ Chang, G Yoon, JS Park, MH Kim… - Biological and …, 2007 - jstage.jst.go.jp
MATERIALS AND METHODS Cell Culture and Viability Assay ECV304 cells, an
immortalized human umbilical vein endothelial cell line, was obtained from the American …
immortalized human umbilical vein endothelial cell line, was obtained from the American …
Differentiation status-dependent regulation of cyclooxygenase-2 expression and prostaglandin E2 production by epidermal growth factor via mitogen-activated protein …
YH Huh, SH Kim, SJ Kim, JS Chun - Journal of Biological Chemistry, 2003 - ASBMB
Although large amounts of epidermal growth factor (EGF) are found in the synovial fluids of
arthritic cartilage, the role of EGF in arthritis is not clearly understood. This study investigated …
arthritic cartilage, the role of EGF in arthritis is not clearly understood. This study investigated …
Crosstalk between p53 and nuclear factor-κB systems: pro-and anti-apoptotic functions of NF-κB
Nuclear factors p53 and NF-κB control many physiological processes including cell cycle
arrest, DNA repair, apoptosis, death, innate and adaptive immune responses, and …
arrest, DNA repair, apoptosis, death, innate and adaptive immune responses, and …