Role of cell signalling involved in induction of apoptosis by benzo [a] pyrene and cyclopenta [c, d] pyrene in Hepa1c1c7 cells
A Solhaug, M Refsnes, JA Holme - Journal of cellular …, 2004 - Wiley Online Library
The reactive metabolites of benzo [a] pyrene (B [a] P) and cyclopenta [c, d] pyrene (CPP)
induced an accumulation/phosphorylation of p53 in Hepa1c1c7 cells, whereas inhibition of …
induced an accumulation/phosphorylation of p53 in Hepa1c1c7 cells, whereas inhibition of …
Paclitaxel inhibits proliferation and promotes apoptosis through regulation ROS and endoplasmic reticulum stress in osteosarcoma cell
M Li, L Yin, L Wu, Y Zhu, X Wang - Molecular & Cellular Toxicology, 2020 - Springer
Background Paclitaxel is a chemotherapeutic drug for cancer, which is isolated from the
Pacific yew tree. However, and the molecular mechanism and the antitumor effects of …
Pacific yew tree. However, and the molecular mechanism and the antitumor effects of …
[PDF][PDF] Effect of 1, 2, 3, 4, 6-penta-O-galloyl-beta-D-glucose on elastase and hyaluronidase activities and its type II collagen expression
In the current era, natural products are gaining prime attention in the fields of cosmeceuticals
and pharmaceuticals due to higher safety margins and biological functions, as they have a …
and pharmaceuticals due to higher safety margins and biological functions, as they have a …
Pectin and soybean meal induce stronger inflammatory responses and dysregulation of bile acid (BA) homeostasis than cellulose and cottonseed meal, respectively …
Q Ni, C Cai, S Ren, J Zhang, Y Zhao, X Wei… - Aquaculture …, 2021 - Wiley Online Library
This study aimed to reveal the impact of excessive dietary fibre (DF) intake on inflammatory
responses and bile acid (BA) homeostasis in largemouth bass (Micropterus salmoides) and …
responses and bile acid (BA) homeostasis in largemouth bass (Micropterus salmoides) and …
Dominant roles of Fenton reaction in sodium nitroprusside-induced chondrocyte apoptosis
YY Quan, GQ Qin, H Huang, YH Liu, XP Wang… - Free Radical Biology …, 2016 - Elsevier
Sodium nitroprusside (SNP) has been widely used as an exogenous nitric oxide (NO) donor
to explore the molecular mechanism of NO-mediated chondrocyte apoptosis during the …
to explore the molecular mechanism of NO-mediated chondrocyte apoptosis during the …
In Vitro Chondrocyte Culture in a Heparin-Based Hydrogel for Cartilage Regeneration
M Kim, Y Shin, BH Hong, YJ Kim, JS Chun… - … Engineering Part C …, 2010 - liebertpub.com
In the present study, we applied and optimized a heparin-based hydrogel system, formed by
thiolated heparin and diacrylated poly (ethylene glycol), for three-dimensional chondrocyte …
thiolated heparin and diacrylated poly (ethylene glycol), for three-dimensional chondrocyte …
Antiapoptotic effects of EGb 761
N Serrano-García, J Pedraza-Chaverri… - Evidence‐Based …, 2013 - Wiley Online Library
Ginkgo biloba extracts have long been used in Chinese traditional medicine for hundreds of
years. The most significant extract obtained from Ginkgo biloba leaves has been EGb 761, a …
years. The most significant extract obtained from Ginkgo biloba leaves has been EGb 761, a …
Nitric oxide‐induced cell death of cerebrocortical murine astrocytes is mediated through p53‐and Bax‐dependent pathways
HW Yung, AK Bal‐Price, GC Brown… - Journal of …, 2004 - Wiley Online Library
We have investigated the mechanism by which nitric oxide (NO) induces the death of mouse
astrocytes. We show that NO (from donor diethylenetriamine‐NO adduct) induces death with …
astrocytes. We show that NO (from donor diethylenetriamine‐NO adduct) induces death with …
Protein kinase Cα and ζ regulate nitric oxide-induced NF-κB activation that mediates cyclooxygenase-2 expression and apoptosis but not dedifferentiation in articular …
SJ Kim, JS Chun - Biochemical and biophysical research communications, 2003 - Elsevier
Nitric oxide (NO) regulates differentiation, survival, and cyclooxygenase (COX)-2 expression
in articular chondrocytes. NO-induced apoptosis and dedifferentiation are mediated by p38 …
in articular chondrocytes. NO-induced apoptosis and dedifferentiation are mediated by p38 …
[HTML][HTML] α-MSH inhibits TNF-α-induced matrix metalloproteinase-13 expression by modulating p38 kinase and nuclear factor κB signaling in human chondrosarcoma …
SW Yoon, JS Chun, MH Sung, JY Kim, H Poo - Osteoarthritis and Cartilage, 2008 - Elsevier
OBJECTIVE: Proinflammatory cytokine-induced expression of matrix metalloproteinases
(MMPs) is a major cause of arthritic cartilage destruction. The neuropeptide, α-melanocyte …
(MMPs) is a major cause of arthritic cartilage destruction. The neuropeptide, α-melanocyte …