Over the last two decades the combination of brain slice patch clamp electrophysiology with
optogenetic stimulation has proven to be a powerful approach to analyze the architecture of …

Depression is the second leading cause of disability in the world population, for which
currently available pharmacological therapies either have poor efficacy or have some …

Synaptic impairment and loss are an important pathological feature of Alzheimer's disease
(AD). Memory is stored in neural networks through changes in synaptic activity, and synaptic …

Aims Major depressive disorder is a severe psychiatric disorder that afflicts~ 17% of the
world population. Neuroimaging investigations of depressed patients have consistently …

Cholecystokinin (CCK) enables excitatory circuit long-term potentiation (LTP). Here, we
investigated its involvement in the enhancement of inhibitory synapses. Activation of GABA …

Understanding neuronal firing patterns and long-term potentiation (LTP) induction in
studying learning, memory, and neurological diseases is critical. However, recently, despite …

The motivation to reproduce is a potent natural drive, and the social behaviors that induce it
can severely impact animal health and lifespan. Indeed, in Drosophila males, accelerated …

The midbrain dopamine system is a sophisticated hub that integrates diverse inputs to
control multiple physiological functions, including locomotion, motivation, cognition, reward …

Comprehensive understanding of the neural circuits involving the ventral tegmental area is
essential for elucidating the anatomo-functional mechanisms governing human behaviour …

Cholecystokinin (CCK) is a neuropeptide modulating digestion, glucose levels,
neurotransmitters and memory. Recent studies suggest that CCK exhibits neuroprotective …