[HTML][HTML] What do we know about inflammatory myofibroblastic tumors?–a systematic review

K Siemion, J Reszec-Gielazyn, J Kisluk… - Advances in Medical …, 2022 - Elsevier
Abstract Background Inflammatory myofibroblastic tumors (IMTs) are rare intermediate-
grade neoplasms that have a high recurrence rate after excision and exhibit low metastatic …

[HTML][HTML] Inflammatory myofibroblastic tumour: state of the art

L Gros, AP Dei Tos, RL Jones, A Digklia - Cancers, 2022 - mdpi.com
Simple Summary Among sarcomas, which are rare cancers, inflammatory myofibroblastic
tumors are extremely rare. Unlike other subtypes, this is a largely oncogene-driven …

Pan-Trk immunohistochemistry is an efficient and reliable screen for the detection of NTRK fusions

JF Hechtman, R Benayed, DM Hyman… - The American journal …, 2017 - journals.lww.com
Activating neurotrophic tyrosine receptor kinase (NTRK) fusions, typically detected using
nucleic-acid based assays, are highly targetable and define certain tumors. Here, we …

Inflammatory myofibroblastic tumor: molecular landscape, targeted therapeutics, and remaining challenges

P Mahajan, M Casanova, A Ferrari, A Fordham… - Current Problems in …, 2021 - Elsevier
Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal tumor of intermediate
malignant potential that predominantly affects children, adolescents and young adults. IMT …

Anaplastic large cell lymphoma: pathology, genetics, and clinical aspects

N Tsuyama, K Sakamoto, S Sakata… - Journal of clinical and …, 2017 - jstage.jst.go.jp
Anaplastic large cell lymphoma (ALCL) was first described in 1985 as a large-cell neoplasm
with anaplastic morphology immunostained by the Ki-1 antibody, which recognizes CD30. In …

ALK Fusions in a Wide Variety of Tumor Types Respond to Anti‐ALK Targeted Therapy

JS Ross, SM Ali, O Fasan, J Block, S Pal… - The …, 2017 - academic.oup.com
Background Genomic fusions of the anaplastic lymphoma kinase gene (ALK) are a well‐
established therapy target in non‐small cell lung cancer (NSCLC). From a survey of 114,200 …

[HTML][HTML] Inflammatory myofibroblastic tumor of the uterus: a clinicopathological, immunohistochemical, and molecular analysis of 13 cases highlighting their broad …

JA Bennett, V Nardi, M Rouzbahman… - Modern Pathology, 2017 - Elsevier
Inflammatory myofibroblastic tumors of the uterus are rare, and although most have a
favorable prognosis, a small subset exhibit extrauterine disease, recur, or cause death. In …

Integrated molecular profiling of juvenile myelomonocytic leukemia

N Murakami, Y Okuno, K Yoshida… - Blood, The Journal …, 2018 - ashpublications.org
Juvenile myelomonocytic leukemia (JMML), a rare and aggressive myelodysplastic/
myeloproliferative neoplasm that occurs in infants and during early childhood, is …

[HTML][HTML] Detection of known and novel ALK fusion transcripts in lung cancer patients using next-generation sequencing approaches

JA Vendrell, S Taviaux, B Béganton, S Godreuil… - Scientific reports, 2017 - nature.com
Rearrangements of the anaplastic lymphoma kinase (ALK) gene in non-small cell lung
cancer (NSCLC) represent a novel molecular target in a small subset of tumors. Although …

[HTML][HTML] USP6 activation in nodular fasciitis by promoter-swapping gene fusions

NR Patel, JSA Chrisinger, EG Demicco, SF Sarabia… - Modern pathology, 2017 - Elsevier
Nodular fasciitis is a self-limited myofibroblastic lesion that can be misdiagnosed as a
sarcoma as a result of its rapid growth, cellularity, and sometimes prominent mitotic activity …