[HTML][HTML] Interleukin-18 cytokine in immunity, inflammation, and autoimmunity: Biological role in induction, regulation, and treatment

SA Ihim, SD Abubakar, Z Zian, T Sasaki… - Frontiers in …, 2022 - frontiersin.org
Interleukin-18 (IL-18) is a potent pro-inflammatory cytokine involved in host defense against
infections and regulates the innate and acquired immune response. IL-18 is produced by …

[HTML][HTML] Autophagy regulates inflammation in intracerebral hemorrhage: Enemy or friend?

K Fu, W Xu, C Lenahan, Y Mo, J Wen… - Frontiers in Cellular …, 2023 - frontiersin.org
Intracerebral hemorrhage (ICH) is the second-largest stroke subtype and has a high
mortality and disability rate. Secondary brain injury (SBI) is delayed after ICH. The main …

[HTML][HTML] Mitophagy in intracerebral hemorrhage: a new target for therapeutic intervention

Y Chen, W Tang, X Huang, Y An, J Li… - Neural Regeneration …, 2024 - journals.lww.com
Intracerebral hemorrhage is a life-threatening condition with a high fatality rate and severe
sequelae. However, there is currently no treatment available for intracerebral hemorrhage …

[HTML][HTML] ATF5 attenuates the secretion of pro-inflammatory cytokines in activated microglia

J Zhu, MJ Lee, JH An, E Oh, W Chung… - International journal of …, 2023 - mdpi.com
The highly dynamic changes in microglia necessary to achieve a rapid neuroinflammatory
response require a supply of energy from mitochondrial respiration, which leads to the …

The crosstalk between immune cells after intracerebral hemorrhage

BW Zhang, KH Sun, T Liu, W Zou - Neuroscience, 2023 - Elsevier
The inflammatory mechanism of intracerebral hemorrhage (ICH) has been widely studied,
and it is believed that the regulation of this mechanism is of great significance to the …

Mechanism of Microglial Cell Activation in the Benzophenone-3 Exposure Model

A Maciejska, B Pomierny, W Krzyżanowska… - Neuroscience, 2023 - Elsevier
Abstract Benzophenone-3 (BP-3) is the most commonly used UV filter in cosmetics, which is
absorbed through the skin and crosses the blood–brain barrier. This compound increases …

Plasmatic profiles of cytokines/chemokines, glial fibrillary acidic protein (GFAP) and MRI brain damage in neonates with hypoxic ischemic encephalopathy (HIE)

C Auriti, V Mondì, F Piersigilli, L Timelli, T Del Pinto… - Cytokine, 2024 - Elsevier
Background Perinatal hypoxia triggers the release of cytokines and chemokines by neurons,
astrocytes and microglia. In response to hypoxia–ischemia resting/ramified microglia …

[HTML][HTML] Association of inflammatory cytokines expression in cerebrospinal fluid with the severity and prognosis of spontaneous intracerebral hemorrhage

T Gu, J Pan, L Chen, K Li, L Wang, Z Zou, Q Shi - BMC neurology, 2024 - Springer
Objective To investigate the potential diagnostic and prognostic implications of inflammatory
cytokine levels in the cerebrospinal fluid (CSF) of patients with spontaneous intracerebral …

抑制小凹蛋白减轻大鼠脑缺血/再灌注诱导的神经功能损伤

陈宁宁, 应新旺, 谢庆凤 - 基础医学与临床, 2022 - journal11.magtechjournal.com
目的探讨小凹蛋白1 (Cav1) 的磷酸化在大鼠脑缺血/再灌注后神经功能损伤中的作用机制.
方法将大鼠随机分为假手术组(sham), 模型组(model) 和抑制剂组(PP2). 用改良神经功能缺损 …

Correlation of Plasmatic Profiles of Inflammatory Cytokines/Chemokines and GFAP with Brain Damage Detected at MRI in Neonates with Hypoxic Ischemic …

C Auriti, F Piersigilli, V Mondì, L Timelli, T Del Pinto… - 2023 - preprints.org
Background & Objective. Perinatal hypoxia acutely triggers the release of cytokines and
chemokines from neurons, astrocytes and microglia. In response to hypoxia-ischemia …