Astrocytes play key roles in the regulation of brain energy metabolism, which has a major
impact on brain functions, including memory, neuroprotection, resistance to oxidative stress …

The elderly population is growing worldwide, with important health and socioeconomic
implications. Clinical and experimental studies on aging have uncovered numerous …

The default mode network (DMN) of the brain is functionally associated with a wide range of
behaviors. In this study, we used functional magnetic resonance imaging (fMRI), positron …

The brain is one of the most energy-consuming organs in the body. Satisfying such energy
demand requires compartmentalized, cell-specific metabolic processes, known to be …

Resting-state functional magnetic resonance imaging (rs-fMRI), which measures the
spontaneous fluctuations in the blood oxygen level-dependent (BOLD) signal, is …

The locus coeruleus (LC) is a region in the brainstem that produces noradrenaline and is
involved in both normal and pathological brain function. Pupillometry, the measurement of …

Dopamine beta‐hydroxylase (DβH) is an essential neurotransmitter‐synthesizing enzyme
that catalyzes the formation of norepinephrine (NE) from dopamine and has been …

Increased astrocytic Ca2+ signaling has been shown in Alzheimer's disease mouse models,
but to date no reports have characterized behaviorally induced astrocytic Ca2+ signaling in …

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease,
characterized by the death of upper (UMN) and lower motor neurons (LMN) in the motor …

The intrinsic activity of the human brain, observed with resting-state fMRI (rsfMRI) and
functional connectivity, exhibits macroscale spatial organization such as functional networks …