Respiratory Dysfunction in Alzheimer's Disease—Consequence or Underlying Cause? Applying Animal Models to the Study of Respiratory Malfunctions

A Wrzesień, K Andrzejewski, M Jampolska… - International Journal of …, 2024 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative brain disease that is the most common
cause of dementia among the elderly. In addition to dementia, which is the loss of cognitive …

[HTML][HTML] Structural changes observed in the piriform cortex in a rat model of pre-motor Parkinson's disease

M Sancandi, EV Schul, G Economides… - Frontiers in cellular …, 2018 - frontiersin.org
Early diagnosis of Parkinson's disease (PD) offers perhaps, the most promising route to a
successful clinical intervention, and the use of an animal model exhibiting symptoms …

Imaging clinical subtypes and associated brain networks in Alzheimer's disease

K Herholz - Brain Sciences, 2022 - mdpi.com
Alzheimer's disease (AD) does not present uniform symptoms or a uniform rate of
progression in all cases. The classification of subtypes can be based on clinical symptoms …

Noradrenergic correlates of chronic cocaine craving: neuromelanin and functional brain imaging

W Wang, S Zhornitsky, S Zhang, CR Li - Neuropsychopharmacology, 2021 - nature.com
Preclinical studies have implicated noradrenergic (NA) dysfunction in cocaine addiction. In
particular, the NA system plays a central role in motivated behavior and may partake in the …

[HTML][HTML] Opposing functions of α-and β-adrenoceptors in the formation of processes by cultured astrocytes

T Kitano, R Eguchi, Y Okamatsu-Ogura… - Journal of …, 2021 - Elsevier
Astrocytes are glial cells with numerous fine processes which are important for the functions
of the central nervous system. The activation of β-adrenoceptors induces process formation …

Redox imbalance and metabolic defects in the context of Alzheimer disease

F Di Domenico, C Lanzillotta, M Perluigi - FEBS letters, 2024 - Wiley Online Library
Redox reactions play a critical role for intracellular processes, including pathways involved
in metabolism and signaling. Reactive oxygen species (ROS) act either as second …

A Parkinson's disease patient displaying increased neuromelanin-sensitive areas in the substantia nigra after rehabilitation with tDCS: A case report

K Ishikuro, N Hattori, R Imanishi, K Furuya, T Nakata… - Neurocase, 2021 - Taylor & Francis
Previous studies have reported that transcranial direct current stimulation (tDCS) of the
frontal polar area (FPA) ameliorated motor disability in patients with Parkinson's disease …

Visual Event-Related Potentials under External Emotional Stimuli as Early Signs for Mild Cognitive Impairment

C Wang, W Yu, T Xu, H Zeng… - The Journal of …, 2024 - Springer
Background Alzheimer's disease (AD) is a neurodegenerative disorder featured by
progressive cognitive decline, which manifests in severe impairment of memory, attention …

[HTML][HTML] Investigating the spontaneous brain activities of patients with subjective cognitive decline and mild cognitive impairment: an amplitude of low-frequency …

Y Gao, S Tian, Y Tang, X Yang, W Dou… - … Imaging in Medicine …, 2023 - ncbi.nlm.nih.gov
Background Subjective cognitive decline (SCD) and mild cognitive impairment (MCI) are
neurodegenerative processing stages of Alzheimer's disease (AD). Cognitive decline is …

Decreased excitability of locus coeruleus neurons during hypercapnia is exaggerated in the streptozotocin-model of Alzheimer's disease

MC Vicente, CM Humphrey, LH Gargaglioni… - Experimental …, 2020 - Elsevier
The locus coeruleus (LC) is a pontine nucleus important for respiratory control and central
chemoreception. It is affected in Alzheimer's disease (AD) and alteration of LC cell function …