Background Malignant tumors have become the most dangerous disease in recent years.
Chemotherapy is the most effective treatment for this disease; however, the problem of drug …

Background Cis-diamminedichloro-platinum (CDDP)-based chemotherapy regimens are the
most predominant treatment strategies for patients with esophageal squamous cell …

Small-molecule drugs are organic compounds affecting molecular pathways by targeting
important proteins, which have a low molecular weight, making them penetrate cells easily …

Background Epidermal growth factor receptor-tyrosinase kinase inhibitor (EGFR-TKI)
resistance is the major obstacle in the treatment of lung adenocarcinoma (LUAD) patients …

According to the global cancer statistic, lung cancer is one of the most dangerous tumors,
which poses a serious threat to human health. Exploration the mechanism of lung cancer …

Multidrug resistance (MDR) is one of the primary factors that produces treatment failure in
patients receiving cancer chemotherapy. MDR is a complex multifactorial phenomenon …

Background Lung adenocarcinoma (LUAD) is currently the leading cause of cancer-related
death worldwide. Long noncoding RNAs (lncRNAs) play key roles in tumor occurrence and …

DNA damage repair (DDR) is critical in maintaining normal cellular function and genome
integrity and is associated with cancer risk, progression, and therapeutic response …

In this review, we provide a general overview of the current panorama of mining strategies
for multi-omics data to investigate lncRNAs with an actual or potential role as biological …

Chemotherapy is a mainstream cancer treatment, but has a constant challenge of drug
resistance, which consequently leads to poor prognosis in cancer treatment. For better …