Non‑small cell lung cancer (NSCLC) is a malignant tumor with a high morbidity and mortality
rate that is a threat to human health. With the development of molecular targeted research …

Thyroid cancers (TCs) are the most common tumors of the endocrine system and a constant
rise in the number of TC cases has been observed for the past few decades. TCs are one of …

Context Comprehensive genomic analysis of thyroid nodules for multiple classes of
molecular alterations detected in a large series of fine needle aspiration (FNA) samples has …

Background: BRAFV600E and N/H/K RAS mutations and oncogenic kinase fusions
involving neurotrophin tyrosine receptor kinase (NTRK), RET, anaplastic lymphoma kinase …

Two-thirds of differentiated thyroid cancer (DTC) patients with distant metastases would be
classified as radioactive iodine-refractory (RAIR-DTC), evolving into a poor outcome. Recent …

Thyroid carcinomas comprise distinct pathologic subtypes. However, advancements in
characterizing the molecular tumorigenesis of thyroid cancers have changed the treatment …

Diffuse sclerosing variant papillary thyroid carcinoma (DS-PTC) is characterized clinically by
a predilection for children and young adults, bulky neck nodes, and pulmonary metastases …

Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer, usually with an
indolent course. ALK fusions are rare in PTC but may give rise to a more aggressive …

Background: Radioiodine (RAI) is commonly used for thyroid cancer treatment, although its
therapeutic benefits are restricted to iodine-avid tumors. The RAI-refractory disease …

Although most follicular-derived thyroid cancers are well differentiated and have an overall
excellent prognosis following treatment with surgery and radioiodine, management of …