Metabolic inflammation and insulin resistance in obesity
H Wu, CM Ballantyne - Circulation research, 2020 - Am Heart Assoc
Obesity is becoming an epidemic in the United States and worldwide and increases risk for
many diseases, particularly insulin resistance, type 2 diabetes mellitus, and cardiovascular …
many diseases, particularly insulin resistance, type 2 diabetes mellitus, and cardiovascular …
[HTML][HTML] Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease
A Chait, LJ Den Hartigh - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …
several types of adipose tissue have been identified, namely white, brown, and beige, that …
Chronic adipose tissue inflammation linking obesity to insulin resistance and type 2 diabetes
Obesity is one of the major health burdens of the 21st century as it contributes to the growing
prevalence of its related comorbidities, including insulin resistance and type 2 diabetes …
prevalence of its related comorbidities, including insulin resistance and type 2 diabetes …
Impact of obesity on influenza A virus pathogenesis, immune response, and evolution
R Honce, S Schultz-Cherry - Frontiers in immunology, 2019 - frontiersin.org
With the rising prevalence of obesity has come an increasing awareness of its impact on
communicable disease. As a consequence of the 2009 H1N1 influenza A virus pandemic …
communicable disease. As a consequence of the 2009 H1N1 influenza A virus pandemic …
Changes in nutritional status impact immune cell metabolism and function
Y Alwarawrah, K Kiernan, NJ MacIver - Frontiers in immunology, 2018 - frontiersin.org
Immune cell function and metabolism are closely linked. Many studies have now clearly
demonstrated that alterations in cellular metabolism influence immune cell function and that …
demonstrated that alterations in cellular metabolism influence immune cell function and that …
Immunological mechanisms and therapeutic targets of fatty liver diseases
Alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) are the two major
types of chronic liver disease worldwide. Inflammatory processes play key roles in the …
types of chronic liver disease worldwide. Inflammatory processes play key roles in the …
Sarcopenic obesity or obese sarcopenia: a cross talk between age-associated adipose tissue and skeletal muscle inflammation as a main mechanism of the …
A Kalinkovich, G Livshits - Ageing research reviews, 2017 - Elsevier
Sarcopenia, an age-associated decline in skeletal muscle mass coupled with functional
deterioration, may be exacerbated by obesity leading to higher disability, frailty, morbidity …
deterioration, may be exacerbated by obesity leading to higher disability, frailty, morbidity …
Immunology in the liver—from homeostasis to disease
The liver is a central immunological organ with a high exposure to circulating antigens and
endotoxins from the gut microbiota, particularly enriched for innate immune cells …
endotoxins from the gut microbiota, particularly enriched for innate immune cells …
Immune and non-immune functions of adipose tissue leukocytes
Adipose tissue is a complex dynamic organ with whole-body immunometabolic influence.
Much of the work into understanding the role of immune cells in adipose tissue has been in …
Much of the work into understanding the role of immune cells in adipose tissue has been in …
The role of infiltrating immune cells in dysfunctional adipose tissue
TJ Guzik, DS Skiba, RM Touyz… - Cardiovascular …, 2017 - academic.oup.com
Adipose tissue (AT) dysfunction, characterized by loss of its homeostatic functions, is a
hallmark of non-communicable diseases. It is characterized by chronic low-grade …
hallmark of non-communicable diseases. It is characterized by chronic low-grade …