Development and validation of a risk prediction nomogram for serious arrhythmias in acute digoxin toxicity among pediatrics: a multicenter study

D El Gameel, AF Sharif, O Shoeib, EI Elgebally… - Toxicon, 2023 - Elsevier
Digoxin is a cardiac glycoside obtained from the leaves of the foxglove plant, Digitalis
lanata. Several studies have described the safety of digoxin including various life …

Pro-Apoptotic and Pro-Autophagic Properties of Cardenolides from Aerial Parts of Pergularia tomentosa

S Martucciello, G Paolella, AM Romanelli, S Sposito… - Molecules, 2022 - mdpi.com
Pergularia tomentosa L., a milkweed tropical plant belonging to the family Asclepiadaceae,
is a rich source of unusual cardiac glycosides, characterised by transfused A/B rings and a …

[HTML][HTML] Proscillaridin A is cytotoxic for glioblastoma cell lines and controls tumor xenograft growth in vivo

E Denicolaï, N Baeza-Kallee, A Tchoghandjian… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Glioblastoma is the most frequent primary brain tumor in adults. Because of molecular and
cellular heterogeneity, high proliferation rate and significant invasive ability, prognosis of …

Digoxin is associated with increased all-cause mortality in patients with atrial fibrillation regardless of concomitant heart failure: a meta-analysis

ZQ Wang, R Zhang, MT Chen, QS Wang… - Journal of …, 2015 - journals.lww.com
For decades, digoxin has been widely used to control ventricular rate in atrial fibrillation
(AF). However, it remains controversial as to whether digoxin is associated with increased …

[PDF][PDF] Национальные рекомендации ВНОК и ОССН по диагностике и лечению ХСН (третий пересмотр)

ВЮ Мареев, ФТ Агеев, ГП Арутюнов… - Журнал сердечная …, 2009 - medvuz.info
В короткой преамбуле хочется предпослать этому докумен ту несколько определяющих
позиций: 1. Принятие в 2003 и 2006 годах съездами ВНОК Нацио нальных …

Update of pediatric heart failure

K Watanabe, R Shih - Pediatric Clinics, 2020 - pediatric.theclinics.com
Pediatric heart failure (PHF) data has wide variation due to the scarcity of large multicenter
studies. Literature is based mostly on single-center publications. A systematic review by …

Age-related differences in the prevalence of potential drug-drug interactions in ambulatory dyslipidaemic patients treated with statins

SS Egger, AER Bravo, L Hess, RG Schlienger… - Drugs & aging, 2007 - Springer
Background and objective Elderly patients may be at higher risk of drug-drug interactions
(DDIs) because of polypharmacy. This study evaluated age-specific differences in the …

Anti-arrhythmic strategies for atrial fibrillation: The role of computational modeling in discovery, development, and optimization

E Grandi, MM Maleckar - Pharmacology & therapeutics, 2016 - Elsevier
Atrial fibrillation (AF), the most common cardiac arrhythmia, is associated with increased risk
of cerebrovascular stroke, and with several other pathologies, including heart failure …

Effect of digoxin on all-cause and cardiovascular mortality in patients with atrial fibrillation with and without heart failure: an umbrella review of systematic reviews and …

G Gazzaniga, D Menichelli, F Scaglione… - European journal of …, 2023 - Springer
Purpose To perform a systematic umbrella review with meta-analysis to evaluate the
certainty of evidence on mortality risk associated with digoxin use in patients with atrial …

Digoxin and reduction in mortality and hospitalization in geriatric heart failure: importance of low doses and low serum concentrations

A Ahmed - The Journals of Gerontology Series A: Biological …, 2007 - academic.oup.com
Background. Digoxin reduces hospitalizations due to heart failure (HF) and may also reduce
mortality at low serum digoxin concentrations (SDC). Most HF patients are≥ 65 years, yet …