UNBS1450: A new hemi‐synthetic cardenolide with promising anti‐cancer activity
T Mijatovic, F Lefranc… - Drug Development …, 2007 - Wiley Online Library
Several reports suggest the sodium pump as an interesting oncology target, given that its
subunit expression is markedly altered in cancer. By binding to the sodium pump …
subunit expression is markedly altered in cancer. By binding to the sodium pump …
Synthesis and evaluation of cardiac glycoside mimics as potential anticancer drugs
M Jensen, S Schmidt, NU Fedosova… - Bioorganic & medicinal …, 2011 - Elsevier
The cardiac glycoside digitoxin, consisting of a steroid core linked to a labile trisaccharide,
has been used for centuries for the treatment of congestive heart failure. The well known …
has been used for centuries for the treatment of congestive heart failure. The well known …
Biotransformation of 21-O-acetyl-deoxycorticosterone by cell suspension cultures of Digitalis lanata (strain W. 1.4)
RM de Pádua, N Meitinger, JD de Souza Filho… - Steroids, 2012 - Elsevier
Cell cultures of Digitalis species are known to accept exogenous substrates for
biotransformation reactions. We here report the biotransformation of 21-O-acetyl …
biotransformation reactions. We here report the biotransformation of 21-O-acetyl …
Impact of digoxin utilization on clinical outcomes following left ventricular assist device implantation
MA Abbasi, DA Stoller, E Lyden… - … Journal of Artificial …, 2022 - journals.sagepub.com
Introduction: We aimed to assess the impact of digoxin use following left ventricular assist
device (LVAD) implantation on clinical outcomes. Methods: Patients implanted with …
device (LVAD) implantation on clinical outcomes. Methods: Patients implanted with …
The safety of digoxin as a pharmacological treatment of atrial fibrillation
Digoxin has traditionally been the drug of choice for ventricular rate control in patients with
chronic atrial fibrillation (AF), with or without heart failure (HF) with systolic dysfunction. In …
chronic atrial fibrillation (AF), with or without heart failure (HF) with systolic dysfunction. In …
Using untargeted LC-MS metabolomics to identify the association of biomarkers in cattle feces with marbling standard longissimus lumborum
D Chen, M Su, H Zhu, G Zhong, X Wang, W Ma… - Animals, 2022 - mdpi.com
Simple Summary To improve the grade of beef marbling has great economic value in the
cattle industry since marbling has the traits of high quality and comprehensive nutrition. This …
cattle industry since marbling has the traits of high quality and comprehensive nutrition. This …
Cardiovascular pharmacogenetics
R Myburgh, WE Hochfeld, TM Dodgen, J Ker… - Pharmacology & …, 2012 - Elsevier
Human genetic variation in the form of single nucleotide polymorphisms as well as more
complex structural variations such as insertions, deletions and copy number variants, is …
complex structural variations such as insertions, deletions and copy number variants, is …
[PDF][PDF] Pharmacologically relevant drug interactions of glucagon-like peptide-1 receptor agonists
NMP Maideen - J Anal Pharm Res, 2019 - researchgate.net
Glucagon-like peptide-1 (GLP-1) receptor agonists are incretin mimetics and they are useful
in the treatment of type 2 diabetes mellitus (Type 2 DM). The drugs such as Exenatide …
in the treatment of type 2 diabetes mellitus (Type 2 DM). The drugs such as Exenatide …