Nonrandomized controlled trial of artesunate plus sulfadoxine-pyrimethamine with or without primaquine for preventing posttreatment circulation of Plasmodium …

NK Shah, A Schapira, JJ Juliano… - Antimicrobial agents …, 2013 - Am Soc Microbiol
Artemisinin combination therapies eliminate immature Plasmodium falciparum gametocytes
but not mature gametocytes, which may persist for up to 1 month posttreatment. A single …

[PDF][PDF] Long term primaquine administration to reduce Plasmodium falciparum gametocyte transmission in hypoendemic areas

P Wilairatana, N Tangpukdee… - Southeast Asian J Trop …, 2010 - tm.mahidol.ac.th
Artemesinin-combination therapies (ACTs) for falciparum malaria reduce gametocyte
carriage, and therefore reduce transmission. Artemisinin derivatives act only against young …

A model for assessing the quantitative effects of heterogeneous affinity in malaria transmission along with ivermectin mass administration

J Sequeira, J Louçã, AM Mendes, PG Lind - Applied Sciences, 2020 - mdpi.com
Using an agent-based model of malaria, we present numerical evidence that in communities
of individuals having an affinity varying within a broad range of values, disease transmission …

Editorial Commentary: Single-Dose Primaquine as Gametocytocidal Treatment in Patients With Uncomplicated Falciparum Malaria

AM Dondorp - Clinical infectious diseases, 2013 - academic.oup.com
The world has seen a significant reduction in the burden of Plasmodium falciparum malaria
over the last decade, which can to a large extent be attributed to the wide deployment of …

[PDF][PDF] Therapeutic Efficacy and Safety of Artemether-Lumefantrine Plus a Single Low-Dose Primaquine for The Treatment of Uncomplicated Plasmodium Falciparum …

M Tadesse - 2023 - ir.bdu.edu.et
Background: Plasmodium species are obligate intracellular protozoan parasites that cause
malaria, which is a major public health problem. One of the most important malaria control …

[HTML][HTML] Effect of Primaquine on Gametocyte Carriage in the Case-Management of Uncomplicated Falciparum Malaria with Acts: Nigerian Perspective

AB Tsuung, SL Pitmang, FL Dassak - Advances in Infectious Diseases, 2018 - scirp.org
Background: Drugs that kill or inhibit sexual stages of Plasmodium such as Primaqiune (PQ)
could potentially amplify or synergize the impact of first line antimalarials by blocking …

A Stochastic Model of Malaria Transmission

JFA Sequeira - 2022 - search.proquest.com
ISTA - School of Technology and Arquitecture A STOCHASTIC MODEL OF MALARIA
TRANSMISSION Joao Fernando Araújo Sequeira PhD in Page 1 ISTA - School of Technology …

Evaluation of the efficacy and safety of primaquine for clearance of gametocytes in uncomplicated falciparum malaria in Uganda

C Eziefula - 2020 - researchonline.lshtm.ac.uk
Background: After standard effective antimalarial treatment with artemisinin-based
combination therapy (ACT), a proportion of individuals remain infectious to mosquitoes …

[PDF][PDF] Pharmacological modelling to investigate antimalarial drug treatment

K Kay - 2013 - core.ac.uk
Malaria remains a major public health concern for billions of people worldwide. Achieving
the ambitious goal of malaria eradication requires co-ordination of control strategies dealing …

[PDF][PDF] Malaria's Missing Number: Calculating the Human Component of R0 by a Within-Host Mechanistic Model of

GL Johnston, DL Smith, DA Fidock - 2013 - academia.edu
Human infection by malarial parasites of the genus Plasmodium begins with the bite of an
infected Anopheles mosquito. Current estimates place malaria mortality at over 650,000 …