Staying true to yourself: mechanisms of DNA methylation maintenance in mammals
DNA methylation is essential to development and cellular physiology in mammals. Faulty
DNA methylation is frequently observed in human diseases like cancer and neurological …
DNA methylation is frequently observed in human diseases like cancer and neurological …
[HTML][HTML] Diverse mechanisms of centromere specification
BG Mellone, D Fachinetti - Current Biology, 2021 - cell.com
The centromere performs a universally conserved function, to accurately partition genetic
information upon cell division. Yet, centromeres are among the most rapidly evolving …
information upon cell division. Yet, centromeres are among the most rapidly evolving …
Variation and evolution of human centromeres: a field guide and perspective
KH Miga, IA Alexandrov - Annual review of genetics, 2021 - annualreviews.org
We are entering a new era in genomics where entire centromeric regions are accurately
represented in human reference assemblies. Access to these high-resolution maps will …
represented in human reference assemblies. Access to these high-resolution maps will …
[HTML][HTML] CENP-B-mediated DNA loops regulate activity and stability of human centromeres
F Chardon, A Japaridze, H Witt, L Velikovsky… - Molecular cell, 2022 - cell.com
Chromosome inheritance depends on centromeres, epigenetically specified regions of
chromosomes. While conventional human centromeres are known to be built of long tandem …
chromosomes. While conventional human centromeres are known to be built of long tandem …
A complete gap-free diploid genome in Saccharum complex and the genomic footprints of evolution in the highly polyploid Saccharum genus
T Wang, B Wang, X Hua, H Tang, Z Zhang, R Gao, Y Qi… - Nature plants, 2023 - nature.com
A diploid genome in the Saccharum complex facilitates our understanding of evolution in the
highly polyploid Saccharum genus. Here we have generated a complete, gap-free genome …
highly polyploid Saccharum genus. Here we have generated a complete, gap-free genome …
Human chromosome‐specific aneuploidy is influenced by DNA‐dependent centromeric features
M Dumont, R Gamba, P Gestraud, S Klaasen… - The EMBO …, 2020 - embopress.org
Intrinsic genomic features of individual chromosomes can contribute to chromosome‐
specific aneuploidy. Centromeres are key elements for the maintenance of chromosome …
specific aneuploidy. Centromeres are key elements for the maintenance of chromosome …
The genome-wide mutational consequences of DNA hypomethylation
N Besselink, J Keijer, C Vermeulen, S Boymans… - Scientific Reports, 2023 - nature.com
DNA methylation is important for establishing and maintaining cell identity and for genomic
stability. This is achieved by regulating the accessibility of regulatory and transcriptional …
stability. This is achieved by regulating the accessibility of regulatory and transcriptional …
[HTML][HTML] Protective role of curcumin on broiler liver by modulating aflatoxin B1-induced DNA methylation and CYPs expression
R Liu, Y Ding, W Li, S Li, X Li, D Zhao, Y Zhang… - Ecotoxicology and …, 2023 - Elsevier
The purpose of this study was to investigate the role of epigenetic DNA methylation and
CYPs expression in AFB1-exposed broiler liver and the protective effect of curcumin. Sixty …
CYPs expression in AFB1-exposed broiler liver and the protective effect of curcumin. Sixty …
A near‐complete assembly of asparagus bean provides insights into anthocyanin accumulation in pods
Y Yang, Z Wu, Z Wu, T Li, Z Shen… - Plant Biotechnology …, 2023 - Wiley Online Library
Asparagus bean (Vigna unguiculata ssp. sesquipedialis), a subspecies of V. unguiculata, is
a vital legume crop widely cultivated in Asia for its tender pods consumed as vegetables …
a vital legume crop widely cultivated in Asia for its tender pods consumed as vegetables …
From evolution to function: Two sides of the same CENP-B coin?
R Gamba, D Fachinetti - Experimental Cell Research, 2020 - Elsevier
The centromere is the nucleoproteic chromosomal structure necessary for accurate
chromosome segregation during cell division. One of the earliest centromeric proteins to be …
chromosome segregation during cell division. One of the earliest centromeric proteins to be …