Cognitive recovery after anaesthesia and surgery is a concern for older adults, their families,
and caregivers. Reports of patients who were 'never the same'prompted a scientific inquiry …

BACKGROUND: We analyzed cases of malignant hyperthermia (MH) reported to the North
American MH Registry for clinical characteristics, treatment, and complications. METHODS …

Background Anaesthetic drugs act at sites within the brain that undergo profound changes
during typical ageing. We postulated that anaesthesia-induced brain dynamics observed in …

As part of the American Society of Anesthesiology Brain Health Initiative goal of improving
perioperative brain health for older patients, over 30 experts met at the fifth International …

Background The effect of volatile anesthetics on cerebral blood flow depends on the
balance between the indirect vasoconstrictive action secondary to flow-metabolism coupling …

Background. The motivation for this study was the current difficulty in estimating the total age‐
related MAC for a patient in a clinical setting. Methods. Age‐related iso‐MAC charts for …

Page 1 Committee on Acute Exposure Guideline Levels Committee on Toxicology Board on
Environmental Studies and Toxicology Division on Earth and Life Studies Page 2 THE …

Introduction The proportion of the elderly is constantly increasing and by the year 2025 20%
of the population will be above 65 years of age. With advanced age, subjects will develop …

Two defining effects of inhaled anesthetics (immobility in the face of noxious stimulation, and
absence of memory) correlate with the end-tidal concentrations of the anesthetics. Such …

Background Impaired cerebral autoregulation may predispose patients to cerebral
hypoperfusion during cardiopulmonary bypass (CPB). The purpose of this study was to …