2019 European Thyroid Association guidelines for the treatment and follow-up of advanced radioiodine-refractory thyroid cancer

L Fugazzola, R Elisei, D Fuhrer, B Jarzab… - European thyroid …, 2019 - etj.bioscientifica.com
The vast majority of thyroid cancers of follicular origin (TC) have a very favourable outcome,
but 5–10% of cases will develop metastatic disease. Around 60–70% of this subset, hence …

Novel targeted therapies and immunotherapy for advanced thyroid cancers

GE Naoum, M Morkos, B Kim, W Arafat - Molecular cancer, 2018 - Springer
Thyroid cancer is a frequently encountered endocrine malignancy. Despite the favorable
prognosis of this disease, 15–20% of differentiated thyroid cancer (DTC) cases and most …

The American Association of Endocrine Surgeons guidelines for the definitive surgical management of thyroid disease in adults

KN Patel, L Yip, CC Lubitz, EG Grubbs, BS Miller… - Annals of …, 2020 - journals.lww.com
Objective: To develop evidence-based recommendations for safe, effective, and appropriate
thyroidectomy. Background: Surgical management of thyroid disease has evolved …

Dissecting anaplastic thyroid carcinoma: a comprehensive clinical, histologic, immunophenotypic, and molecular study of 360 cases

B Xu, T Fuchs, S Dogan, I Landa, N Katabi, JA Fagin… - Thyroid, 2020 - liebertpub.com
Background: Anaplastic thyroid carcinoma (ATC) is nearly always fatal. Large studies on
ATC are exceedingly rare. We aimed to study the clinical, genotypic, and histologic …

Primary high‐grade non‐anaplastic thyroid carcinoma: a retrospective study of 364 cases

B Xu, J David, S Dogan, I Landa, N Katabi… - …, 2022 - Wiley Online Library
Aims We aimed to study the clinicopathological and molecular features of high‐grade non‐
anaplastic thyroid carcinomas (HGTCs), a carcinoma with a prognosis intermediate between …

Molecular alterations in thyroid carcinoma

MRH Al Rasheed, B Xu - Surgical pathology clinics, 2019 - surgpath.theclinics.com
Thyroid carcinoma is the most common cancer in the endocrine system. Recent advances,
using next-generation sequencing, have shed light on the molecular pathogenesis of thyroid …

Special types of thyroid carcinoma

ZW Baloch, VA LiVolsi - Histopathology, 2018 - Wiley Online Library
This article reviews the small percentage of thyroid tumours that are not classified as classic
papillary thyroid carcinoma, follicular thyroid carcinoma, and medullary thyroid carcinoma. It …

Real-world experience with targeted therapy for the treatment of anaplastic thyroid carcinoma

PC Iyer, R Dadu, R Ferrarotto, NL Busaidy, MA Habra… - Thyroid, 2018 - liebertpub.com
Background: Patients with anaplastic thyroid cancer (ATC) have a dismal prognosis, despite
systemic cytotoxic chemotherapy. The objective of this study was to investigate the efficacy …

Spectrum of TERT promoter mutations and mechanisms of activation in thyroid cancer

F Panebianco, AV Nikitski, MN Nikiforova… - Cancer …, 2019 - Wiley Online Library
Background Reactivation of telomerase reverse transcriptase (TERT) is an important event
in cancer. Two hotspot mutations in the TERT promoter region, c.‐124C> T (C228T) and c …

Anaplastic thyroid carcinoma: an epidemiologic, histologic, immunohistochemical, and molecular single-institution study

A Deeken-Draisey, GY Yang, J Gao, BA Alexiev - Human pathology, 2018 - Elsevier
Anaplastic thyroid carcinoma (ATC) is a highly aggressive form of thyroid cancer. A single-
institution thyroid cancer cohort of ATC was identified within the last 10 years at our …