Case report and literature review: management of Paxlovid (nirmatrelvir/ritonavir)-induced acute tacrolimus toxicity in a patient with systemic lupus erythematosus
C Jiang, X Yan, P Xia, X Luo, H Zheng… - Frontiers in …, 2024 - frontiersin.org
Despite the availability of effective vaccines and treatments for SARS-CoV-2, managing
COVID-19 in patients with systemic lupus erythematosus (SLE) remains challenging …
COVID-19 in patients with systemic lupus erythematosus (SLE) remains challenging …
Case report: Paralytic ileus resulted from nirmatrelvir/ritonavir-tacrolimus drug-drug interaction in a systemic lupus erythematosus patient with COVID-19
W Zhang, X Zhang, J Han, W Zhang, J Xu… - Frontiers in …, 2024 - frontiersin.org
Patients with systemic autoimmune rheumatic diseases are at a high risk for severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and effective antiviral …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and effective antiviral …
The effects of nirmatrelvir/ritonavir on tacrolimus levels in lung transplant recipients: A single-center study
X Wang, W Du, D Zhang, W Chen, X Zuo - Pulmonary Pharmacology & …, 2024 - Elsevier
Abstract Background Lung transplant recipients (LTRs) have a higher risk of hospitalization
and mortality due to COVID-19 compared with the immunocompetent population. The use of …
and mortality due to COVID-19 compared with the immunocompetent population. The use of …
Effect of rifampicin administration on CYP induction in a dermatomyositis patient with vasospastic angina attributable to nilmatrelvir/ritonavir-induced blood tacrolimus …
H Akamatsu, Y Kohno, J Hashizume… - Journal of Infection and …, 2024 - Elsevier
Ritonavir (RTV), which is used in combination with nilmatrelvir (NMV) to treat coronavirus
disease 2019 (COVID-19), inhibits cytochrome P450 (CYP) 3A, thereby increasing blood …
disease 2019 (COVID-19), inhibits cytochrome P450 (CYP) 3A, thereby increasing blood …
Rescue Therapy for Supratherapeutic Concentrations of Calcineurin Inhibitors Using Potent Cytochrome P450 Inducers
S Duwor, K Enthofer, C Ganter, P Poudel… - …, 2024 - mdpi.com
Introduction: Calcineurin inhibitors (CNIs), ciclosporin and tacrolimus, are utilized primarily
in organ transplantation and the treatment of autoimmune diseases. Since patients depend …
in organ transplantation and the treatment of autoimmune diseases. Since patients depend …
[PDF][PDF] Wei Zhang1, 2*, Xingguo Zhang2, 3, Jinming Han2, Wen Zhang4, Jiarui Xu2, 3, Xin Zhang2, Hongjun Bian2, Chong Meng2, Deya Shang2, Yi Zhou2, Dawei …
B Feng, W Zhang, X Zhang, J Han, J Xu, H Bian… - 2024 - scienceopen.com
Patients with systemic autoimmune rheumatic diseases (SARD) are at a high risk for severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in terms of morbidity and …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in terms of morbidity and …