In adipocytes the hydrolysis of TAG to produce fatty acids and glycerol under fasting
conditions or times of elevated energy demands is tightly regulated by neuroendocrine …

Obesity has been steadily increasing over the past decade in the US and worldwide. Since
1975, the prevalence of obesity has increased by 2% per decade, unabated despite new …

Background Parallel to growth of aging and obese populations, the prevalence of metabolic
diseases is rising. How body mass index (BMI) relates to frailty and mortality across frailty …

Obesity is the accumulation of abnormal or excessive fat that may interfere with the
maintenance of an optimal state of health. The excess of macronutrients in the adipose …

Although excess visceral fat is associated with noninfectious inflammation, it is not clear
whether visceral fat is simply associated with or actually causes metabolic disease in …

Obesity is a major health problem and a risk factor for type 2 diabetes. Leptin, an adipocyte-
secreted hormone, acts on the hypothalamus to inhibit food intake and increase energy …

Obesity is defined as an accumulation of excessive amounts of adipose tissue in the body,
and has been called the most common nutritional disease of dogs in Western countries. 1–5 …

Obesity and its associated disorders are a growing epidemic across the world. Many
genetic, physiological, and behavioral factors play a role in the etiology of obesity. Diet and …

There is extensive evidence supporting the interference of inflammatory activation with
metabolism. Obesity, mainly visceral obesity, is associated with a low‐grade inflammatory …

Obesity is an exaggeration of normal adiposity and is a central player in the pathophysiology
of diabetes mellitus, insulin resistance, dyslipidemia, hypertension, and atherosclerosis …