Abstract Alzheimer's disease (AD), a progressive neurodegenerative disorder, is
characterized by the deficits in the cholinergic system and deposition of beta amyloid (Aβ) in …

Acetylcholinesterase is a member of the α/β hydrolase protein super family, with a significant
role in acetylcholine-mediated neurotransmission. Research in the modulators of AChEs …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the central
nervous system (CNS) which is the most common cause of dementia in the elderly. It is …

There are three major active sites of butyrylcholinesterase: catalytic site, peripheral site, and
activator site. In this study, pseudosubstrate inhibitors, 1, 3, 5-alkylcarbamyloxybenzenes (1 …

Phenyl carbamates are used to treat Alzheimer's disease. These compounds inhibit
acetylcholinesterase and butyrylcholinesterase. The goal of this work was to determine the …

Acyloxy‐biphenyl‐4′‐N‐butylcarbamates (1–8) are synthesized from 4, 4′‐biphenol by
two‐step reactions. Carbamates 1–7 are characterized as the pseudo‐substrate inhibitors of …

Alzheimer's disease (AD) is an irreversible, progressive brain disorder that slowly destroys
the memory and the thinking skills, and eventually the ability to carry out the simplest tasks …

Abstract Biphenyl‐4‐acyoxylate‐4′‐N‐butylcarbamates 1–8 are synthesized from 4, 4′‐
biphenol and are characterized as the pseudosubstrate inhibitors of acetylcholinesterase. In …

The kinetic studies and drug designs of butyrylcholinesterase play an important role in the
development of Alzheimer's disease therapeutics. In this research, automated docking …

The acetylcholinesterase inhibition by enantiomers of exo‐and endo‐2‐norbornyl‐N‐n‐
butylcarbamates shows high stereoselelectivity. For the acetylcholinesterase inhibitions by …