The mechanism of stimulating and mobilizing the immune system enhancing the anti-tumor immunity
Z Wu, S Li, X Zhu - Frontiers in immunology, 2021 - frontiersin.org
Cancer immunotherapy is a kind of therapy that can control and eliminate tumors by
restarting and maintaining the tumor-immune cycle and restoring the body's normal anti …
restarting and maintaining the tumor-immune cycle and restoring the body's normal anti …
EZH2 function in immune cell development
The polycomb repressive complex 2 (PRC2) consists of three core components EZH2,
SUZ12 and EED. EZH2 catalyzes the methylation of lysine 27 of histone H3, a modification …
SUZ12 and EED. EZH2 catalyzes the methylation of lysine 27 of histone H3, a modification …
Understanding cervical cancer at single-cell resolution
Cervical cancer is now the fourth most prevalent malignancy in women worldwide,
representing a tremendous burden of cancer. The heterogeneity of complex tumor …
representing a tremendous burden of cancer. The heterogeneity of complex tumor …
[HTML][HTML] Recent advances in iNKT cell development
K Hogquist, H Georgiev - F1000Research, 2020 - ncbi.nlm.nih.gov
Recent studies suggest that murine invariant natural killer T (iNKT) cell development
culminates in three terminally differentiated iNKT cell subsets denoted as NKT1, 2, and 17 …
culminates in three terminally differentiated iNKT cell subsets denoted as NKT1, 2, and 17 …
[HTML][HTML] Brief homogeneous TCR signals instruct common iNKT progenitors whose effector diversification is characterized by subsequent cytokine signaling
S Bortoluzzi, N Dashtsoodol, T Engleitner, C Drees… - Immunity, 2021 - cell.com
Innate-like T cell populations expressing conserved TCRs play critical roles in immunity
through diverse developmentally acquired effector functions. Focusing on the prototypical …
through diverse developmentally acquired effector functions. Focusing on the prototypical …
Przewalcyrones A–F, epoxychromene-containing polycyclic polyprenylated acylphloroglucinols with immunosuppressive activity from Hypericum przewalskii Maxim.
Y Duan, S Xie, Y Guo, Y Qiao, Z Shi, L Tao… - Organic & …, 2019 - pubs.rsc.org
Chemical investigation of the extracts of the aerial parts of Hypericum przewalskii Maxim.
resulted in the isolation and identification of six new epoxychromene-containing polycyclic …
resulted in the isolation and identification of six new epoxychromene-containing polycyclic …
Reduction of peripheral blood iNKT and γδT cells in patients with Parkinson's disease: an observational study
C Zhou, X Zhou, D He, Z Li, X Xie, Y Ren - Frontiers in immunology, 2020 - frontiersin.org
Objective: To investigate the frequencies and numbers of invariant natural killer T (iNKT)
cells and γδT cells in the peripheral blood of patients with the Parkinson's disease (PD), and …
cells and γδT cells in the peripheral blood of patients with the Parkinson's disease (PD), and …
Nur77 controls tolerance induction, terminal differentiation, and effector functions in semi-invariant natural killer T cells
A Kumar, TM Hill, LE Gordy… - Proceedings of the …, 2020 - National Acad Sciences
Semi-invariant natural killer T (iNKT) cells are self-reactive lymphocytes, yet how this lineage
attains self-tolerance remains unknown. iNKT cells constitutively express high levels of …
attains self-tolerance remains unknown. iNKT cells constitutively express high levels of …
Classical MHC expression by DP thymocytes impairs the selection of non-classical MHC restricted innate-like T cells
Conventional T cells are selected by peptide-MHC expressed by cortical epithelial cells in
the thymus, and not by cortical thymocytes themselves that do not express MHC I or MHC II …
the thymus, and not by cortical thymocytes themselves that do not express MHC I or MHC II …
Alteration of circulating unconventional T cells in cerebral ischemia: an observational study
C Zhou, W Rao, X Zhou, D He, Z Li, N Dashtsoodol… - Scientific Reports, 2022 - nature.com
Immune reactions provoked by cerebral ischemia play crucial roles in the pathogenesis of
brain damage and contribute to tissue regeneration processes. While functions of many …
brain damage and contribute to tissue regeneration processes. While functions of many …