Nanodiscs in membrane biochemistry and biophysics

IG Denisov, SG Sligar - Chemical reviews, 2017 - ACS Publications
Membrane proteins play a most important part in metabolism, signaling, cell motility,
transport, development, and many other biochemical and biophysical processes which …

Folding and misfolding of human membrane proteins in health and disease: from single molecules to cellular proteostasis

JT Marinko, H Huang, WD Penn, JA Capra… - Chemical …, 2019 - ACS Publications
Advances over the past 25 years have revealed much about how the structural properties of
membranes and associated proteins are linked to the thermodynamics and kinetics of …

The All E. coli TX-TL Toolbox 2.0: A Platform for Cell-Free Synthetic Biology

J Garamella, R Marshall, M Rustad… - ACS synthetic …, 2016 - ACS Publications
We report on and provide a detailed characterization of the performance and properties of a
recently developed, all Escherichia coli, cell-free transcription and translation system. Gene …

Nanodiscs: A toolkit for membrane protein science

SG Sligar, IG Denisov - Protein Science, 2021 - Wiley Online Library
Membrane proteins are involved in numerous vital biological processes, including transport,
signal transduction and the enzymes in a variety of metabolic pathways. Integral membrane …

Lipid membrane mimetics in functional and structural studies of integral membrane proteins

S Majeed, AB Ahmad, U Sehar, ER Georgieva - Membranes, 2021 - mdpi.com
Integral membrane proteins (IMPs) fulfill important physiological functions by providing cell–
environment, cell–cell and virus–host communication; nutrients intake; export of toxic …

An integrated framework advancing membrane protein modeling and design

RF Alford, J Koehler Leman, BD Weitzner… - PLoS computational …, 2015 - journals.plos.org
Membrane proteins are critical functional molecules in the human body, constituting more
than 30% of open reading frames in the human genome. Unfortunately, a myriad of …

Droplet microfluidics for the construction of compartmentalised model membranes

T Trantidou, MS Friddin, A Salehi-Reyhani, O Ces… - Lab on a Chip, 2018 - pubs.rsc.org
The design of membrane-based constructs with multiple compartments is of increasing
importance given their potential applications as microreactors, as artificial cells in synthetic …

Minimal out-of-equilibrium metabolism for synthetic cells: a membrane perspective

E Bailoni, M Partipilo, J Coenradij… - ACS Synthetic …, 2023 - ACS Publications
Life-like systems need to maintain a basal metabolism, which includes importing a variety of
building blocks required for macromolecule synthesis, exporting dead-end products, and …

Liposome display for in vitro selection and evolution of membrane proteins

S Fujii, T Matsuura, T Sunami, T Nishikawa, Y Kazuta… - Nature protocols, 2014 - nature.com
Liposome display is a novel method for in vitro selection and directed evolution of
membrane proteins. In this approach, membrane proteins of interest are displayed on …

Liposomes: targeted and controlled delivery system

T Garg, AK Goyal - Drug delivery letters, 2014 - ingentaconnect.com
Novel drug delivery systems (NDDS) delivered the active molecules to the target site in a
defined manner for produce the desired effects without disturbing the delicate bio …