In contrast to the major families of small molecules and antibodies, cyclic peptides, as a
family of synthesizable macromolecules, have distinct biochemical and therapeutic …

Flavonoids are a category of plant-derived compounds which exhibit a large number of
health-related effects. One of the most well-known and studied flavonoids is kaempferol …

Annually, over 150 million severe cases of fungal infections occur worldwide, resulting in
approximately 1.7 million deaths per year. Alarmingly, these numbers are continuously on …

Background Flavonols are one of the most promising class of bioactive compounds
belonging to the broad family of the flavonoids, characterized by a unique set of features in …

Background The global burden of invasive fungal infections (IFIs) has shown an upsurge in
recent years due to the higher load of immunocompromised patients suffering from various …

With increasing number of immunocompromised patients as well as drug resistance in fungi,
the risk of fatal fungal infections in humans increases as well. The action of echinocandins is …

Microbial infections endanger human health and life. Conventional antibiotics has saved
countless human lives, however, is seriously challenged by the quick emergence of …

Fungal infections, named mycosis, can cause severe invasive and systemic diseases that
can even lead to death. In recent years, epidemiological data have recorded an increase in …

Fungi produce millions of clonal asexual conidia (spores) that remain dormant until
favourable conditions occur. Conidia contain abundant stable messenger RNAs but the …

The high mortality rate of invasive fungal infections and quick emergence of drug-resistant
fungal pathogens urgently call for potent antifungal agents. Inspired by the cell penetrating …