Abstract Of the~ 129,079 new cases of nasopharyngeal carcinoma (NPC) and 72,987
associated deaths estimated for 2018, the majority will be geographically localized to South …

Current knowledge is insufficient to explain why only a proportion of individuals exposed to
environmental carcinogens or carrying a genetic predisposition to cancer develop disease …

While infection with Epstein–Barr virus (EBV) is known to be an essential risk factor for the
development of nasopharyngeal carcinoma (NPC), other co-factors including genetic factors …

Common understanding suggests that the normal function of a “healthy” immune system
safe-guards and protects against the development of malignancies, whereas a genetically …

Interactions of killer cell immunoglobin-like receptors (KIR) with human leukocyte antigens
(HLA) class I regulate effector functions of key cytotoxic cells of innate and adaptive …

Nasopharyngeal carcinoma (NPC) is an epithelial malignancy facilitated by Epstein-Barr
Virus infection. Here we resolve the major genetic influences for NPC incidence using a …

Nasopharyngeal carcinoma (NPC) results from the aberrant and uncontrolled growth of the
nasopharyngeal epithelium. It is highly associated with the Epstein–Barr virus, especially in …

The interplay between host cell genetics and Epstein-Barr virus (EBV) infection contributes
to the development of nasopharyngeal carcinoma (NPC). Understanding the host genetic …

Despite pronounced associations of major histocompatibility complex (MHC) regions with
nasopharyngeal carcinoma (NPC), causal variants underlying NPC pathogenesis remain …

Nasopharyngeal carcinoma (NPC) arises from the mucosal epithelium of the nasopharynx
and is constantly associated with Epstein–Barr virus type 1 (EBV‐1) infection. We carried out …