Drugs for neuroprotection after birth asphyxia: pharmacologic adjuncts to hypothermia

F van Bel, F Groenendaal - Seminars in perinatology, 2016 - Elsevier
An adverse outcome is still encountered in 45% of full-term neonates with perinatal asphyxia
who are treated with moderate hypothermia. At present pharmacologic therapies are …

[HTML][HTML] Perinatal hypoxic-ischemic damage: review of the current treatment possibilities

A Frajewicki, Z Laštůvka, V Borbelyova… - Physiological …, 2020 - ncbi.nlm.nih.gov
Neonatal hypoxic-ischemic encephalopathy is a disorder with heterogeneous manifestation
due to asphyxia during perinatal period. It affects approximately 3–12 children per 1000 live …

[HTML][HTML] Erythropoietin pathway: a potential target for the treatment of depression

C Ma, F Cheng, X Wang, C Zhai, W Yue, Y Lian… - International journal of …, 2016 - mdpi.com
During the past decade, accumulating evidence from both clinical and experimental studies
has indicated that erythropoietin may have antidepressant effects. In addition to the kidney …

Erythropoietin improves histological and functional outcomes after traumatic brain injury in mice in the absence of the neural erythropoietin receptor

Y Xiong, A Mahmood, C Qu, H Kazmi… - Journal of …, 2010 - liebertpub.com
Erythropoietin (EPO), essential for erythropoiesis, provides neuroprotection. The EPO
receptor (EPOR) is expressed in both neural and non-neural cells in the brain. This study …

Erythropoietin promotes hippocampal neurogenesis in in vitro models of neonatal stroke

D Osredkar, JW Sall, PE Bickler, DM Ferriero - Neurobiology of disease, 2010 - Elsevier
The hippocampus is often injured in neonatal stroke. We have investigated the effect of
erythropoietin (EPO) on oxygen-glucose deprived hippocampal slices and hypoxic …

[HTML][HTML] Lactoferrin induces erythropoietin synthesis and rescues cognitive functions in the offspring of rats subjected to prenatal hypoxia

AV Sokolov, NM Dubrovskaya, VA Kostevich… - Nutrients, 2022 - mdpi.com
The protective effects of recombinant human lactoferrin rhLF (branded “CAPRABEL™”) on
the cognitive functions of rat offspring subjected to prenatal hypoxia (7% O2, 3 h, 14th day of …

[HTML][HTML] Beneficial effect of erythropoietin on sensorimotor function and white matter after hypoxia-ischemia in neonatal mice

X Fan, CJ Heijnen, MA Van Der Kooij… - Pediatric …, 2011 - nature.com
There are mixed reports on the neuroprotective properties of erythropoietin (EPO) in animal
models of birth asphyxia. We investigated the effect of EPO on short-and long-term outcome …

Factors associated with the development of anemia after subarachnoid hemorrhage

TR Sampson, R Dhar, MN Diringer - Neurocritical care, 2010 - Springer
Introduction Anemia is common after subarachnoid hemorrhage (SAH) and may exacerbate
the reduction in oxygen delivery that underlies delayed cerebral ischemia. Fall in …

[HTML][HTML] Synergistic effect in neurological recovery via anti-apoptotic akt signaling in umbilical cord blood and erythropoietin combination therapy for neonatal hypoxic …

JI Choi, JW Choi, KH Shim, JS Choung, HJ Kim… - International Journal of …, 2021 - mdpi.com
Our previous clinical studies demonstrated the synergistic therapeutic effect induced by co-
administering recombinant human erythropoietin (rhEPO) in human umbilical cord blood …

[HTML][HTML] The role of ketone bodies in various animal models of kidney disease

H Liu, LJ Yan - Endocrines, 2023 - mdpi.com
The kidney is a vital organ that carries out significant metabolic functions in our body. Due to
the complexity of its role, the kidney is also susceptible to many disease conditions, such as …