In humans, the thyroid hormones T3 and T4 are synthesized in the thyroid gland in a
process that crucially involves the iodoglycoprotein thyroglobulin. The overall structure of …

Background The incidence of thyroid cancer has risen dramatically in the United States over
the past four decades, with similar patterns observed internationally. Thyroid cancer …

Thyroid stimulating hormone (TSH) is critical for normal development and metabolism. To
better understand the genetic contribution to TSH levels, we conduct a GWAS meta-analysis …

Background Many pesticides are known to have thyroid-disrupting properties. However, few
studies have evaluated the association between specific pesticide ingredients and risk of …

In this study, we aimed to evaluate site-specific cancer risks associated with hyperthyroidism
or hypothyroidism. We performed a systematic review of observational studies reporting …

Context Thyroid nodules, adenomas, and goiter have consistently been associated with
thyroid cancer risk. Few studies have assessed whether thyroid dysfunction and thyroid …

Whether thyroid dysfunction plays a causal role in the development of cancer remains
inconclusive. We conducted a two‐sample Mendelian randomization study to investigate the …

An ever-increasing population of patients with papillary thyroid cancer is engaging with
health care systems around the world. Numerous questions about optimal management …

The incidence of thyroid cancer (TC) has increased rapidly worldwide in recent years.
Exposure to endocrine disruptors can affect thyroid hormones and is probably carcinogenic …

Benefits of the omega-3 polyunsaturated fatty acids (PUFA) on a number of clinical
disorders, including autoimmune diseases, are widely reported in the literature. One major …