The transforming growth factor beta (TGF‐β) family forms a group of three isoforms, TGF‐β1,
TGF‐β2, and TGF‐β3, with their structure formed by interrelated dimeric polypeptide chains …

Introduction: Successful healing of large bone defects (LBDs) is a complicated phenomenon
because the body's natural ability often fails to effectively repair the LBDs. New modalities …

Purpose The treatment of large bone defects represents a significant challenge for
orthopaedic surgeons. In recent years, biologic agents have also been used to further …

Introduction The aims of this study were to determine the effects of different concentrations of
platelet-rich plasma (PRP) on alveolar bone density and orthodontic tooth movement …

Despite significant advances in the understanding and delivery of osteosynthesis, fracture
non-union remains a challenging clinical problem in orthopaedic surgery. To bridge the gap …

Background Treatment of large bone defects and fracture healing complications (delayed
and non-union) presents a substantial challenge for orthopaedic surgeons. Given that bone …

High tibial osteotomy (HTO) is a widely accepted and performed procedure to treat medial
knee arthrosis. The aim of this review is to evaluate the different surgical options in medial …

Objectives To evaluate the effects of submucosally administered platelet-rich plasma (PRP)
on the rate of maxillary canine retraction. Levels of soluble receptor activator of nuclear …

Background Autologous platelet-rich concentrates (PRCs) are recently used as a local
biological substance in orthodontics to accelerate the rate of tooth movement. Objectives …

The quality of hematomas are crucial for successful early bone defect healing, as the
structure of fibrin clots can significantly influence the infiltration of cells, necessary for bone …