Background The aim of this study was to assess the associations of modifiable lifestyle
factors (smoking, coffee consumption, sleep, and physical activity) and cardiometabolic …

Daytime napping is a common, heritable behavior, but its genetic basis and causal
relationship with cardiometabolic health remain unclear. Here, we perform a genome-wide …

Background Both depression and breast cancer (BC) contribute to a substantial global
burden of morbidity and mortality among women, and previous studies have observed a …

Summary Three-dimensional (3D) chromatin organization maps help dissect cell-type-
specific gene regulatory programs. Furthermore, 3D chromatin maps contribute to …

The military lifestyle often includes continuous operations whether in training or deployed
environments. These stressful environments present unique challenges for service members …

Excessive daytime sleepiness (EDS) affects 10–20% of the population and is associated
with substantial functional deficits. Here, we identify 42 loci for self-reported daytime …

Background Observational studies have found that both short and long sleep duration are
associated with increased risk of metabolic syndrome (MetS). This study aimed to examine …

Timing and duration of sleep are controlled by the circadian system, which keeps an~ 24-h
internal rhythm that entrains to environmental stimuli, and the sleep homeostat, which rises …

Background Sleep problems are both symptoms of and modifiable risk factors for many
psychiatric disorders. Wrist-worn accelerometers enable objective measurement of sleep at …

Background Studies have found sleeping behaviors, such as sleep duration, to be
associated with kidney function and cardiovascular disease risk. However, whether short or …