Alzheimer's disease (AD) is characterized by the accumulation of hyperphosphorylated tau
and amyloid-β (Aβ) protein resulting in synaptic loss and apoptosis. Aβ and tau deposition …

Alzheimer's disease (AD) is a common neurodegenerative disorder in the elderly
characterized by memory loss and cognitive dysfunction. The pathogenesis of AD is …

The pathogenetic mechanisms underlying neuronal death and dysfunction in Alzheimer's
disease (AD) remain unclear. However, chronic neuroinflammation has been implicated in …

Ginseng has been used in China as a superior medicinal material for thousands of years
that can nourish the five internal organs, calm the mind and benefit wisdom. Due to its anti …

Traditionally, mitochondria are known as" the powerhouse of the cell," responsible for
energy (ATP) generation (by the electron transport chain, oxidative phosphorylation, the …

Introduction Alzheimer's disease (AD) is the most prevalent cause of dementia, and
emerging evidence suggests that ferroptosis is involved in the pathological process of AD …

Accumulating evidences reveal that cellular cholesterol deficiency could trigger the onset of
Alzheimer's disease (AD). As a key regulator, 24-dehydrocholesterol reductase (DHCR24) …

Iron plays a crucial role in many physiological processes of the human body, but iron is
continuously deposited in the brain as we age. Early studies found iron overload is directly …

Ganoderic acid A (GAA) is a kind of lanostane-type triterpenoid isolated from Ganoderma
lucidum. Imbalance of the Th17/Tregs axis exists in the progress of neuroinflammation of …

It is estimated that, at minimum, 500 million individuals suffer from cellular metabolic
dysfunction, such as diabetes mellitus (DM), throughout the world. Even more concerning is …