Structure and function of the archaeal response regulator CheY

TEF Quax, F Altegoer, F Rossi, Z Li… - Proceedings of the …, 2018 - National Acad Sciences
Motility is a central feature of many microorganisms and provides an efficient strategy to
respond to environmental changes. Bacteria and archaea have developed fundamentally …

[HTML][HTML] Repurposing a chemosensory macromolecular machine

DR Ortega, W Yang, P Subramanian, P Mann… - Nature …, 2020 - nature.com
How complex, multi-component macromolecular machines evolved remains poorly
understood. Here we reveal the evolutionary origins of the chemosensory machinery that …

Cellular structural biology as revealed by cryo-electron tomography

RN Irobalieva, B Martins, O Medalia - Journal of cell science, 2016 - journals.biologists.com
Understanding the function of cellular machines requires a thorough analysis of the
structural elements that underline their function. Electron microscopy (EM) has been pivotal …

A comprehensive history of motility and Archaellation in Archaea

KF Jarrell, SV Albers, JNS Machado - FEMS microbes, 2021 - academic.oup.com
Each of the three Domains of life, Eukarya, Bacteria and Archaea, have swimming structures
that were all originally called flagella, despite the fact that none were evolutionarily related to …

Baseplate variability of Vibrio cholerae chemoreceptor arrays

W Yang, A Alvarado, T Glatter… - Proceedings of the …, 2018 - National Acad Sciences
The chemoreceptor array, a remarkably ordered supramolecular complex, is composed of
hexagonally packed trimers of receptor dimers networked by a histidine kinase and one or …

Chemotaxis cluster 1 proteins form cytoplasmic arrays in Vibrio cholerae and are stabilized by a double signaling domain receptor DosM

A Briegel, DR Ortega, P Mann, A Kjær… - Proceedings of the …, 2016 - National Acad Sciences
Nearly all motile bacterial cells use a highly sensitive and adaptable sensory system to
detect changes in nutrient concentrations in the environment and guide their movements …

[PDF][PDF] An oscillating MinD protein determines the cellular positioning of the motility machinery in archaea

P Nußbaum, S Ithurbide, JC Walsh, M Patro, F Delpech… - Current Biology, 2020 - cell.com
MinD proteins are well studied in rod-shaped bacteria such as E. coli, where they display
self-organized pole-to-pole oscillations that are important for correct positioning of the Z-ring …

The chemosensory systems of Vibrio cholerae

DR Ortega, A Kjær, A Briegel - Molecular microbiology, 2020 - Wiley Online Library
Vibrio cholerae, the causative agent of the acute diarrheal disease cholera, is able to thrive
in diverse habitats such as natural water bodies and inside human hosts. To ensure their …

Recent advances and future prospects in bacterial and archaeal locomotion and signal transduction

SL Bardy, A Briegel, S Rainville, T Krell - Journal of Bacteriology, 2017 - Am Soc Microbiol
The structure and function of two-component and chemotactic signaling and different
aspects related to the motility of bacteria and archaea are key research areas in modern …

[HTML][HTML] Towards elucidating the rotary mechanism of the archaellum machinery

J Nuno de Sousa Machado, SV Albers… - Frontiers in …, 2022 - frontiersin.org
Motile archaea swim by means of a molecular machine called the archaellum. This structure
consists of a filament attached to a membrane-embedded motor. The archaellum is found …