Aortic aneurysms are a common vascular disease in Western populations that can involve
virtually any portion of the aorta. Abdominal aortic aneurysms are much more common than …

Abdominal aortic aneurysm (AAA) refers to the localized dilatation of the infra-renal aorta, in
which the diameter exceeds 3.0 cm. Loss of vascular smooth muscle cells, degradation of …

Adverse cardiac remodeling following myocardial infarction (MI) remains a significant cause
of congestive heart failure. Additional and novel strategies that improve our ability to predict …

Extracellular matrix (ECM) remodeling is one of the underlying mechanisms in
cardiovascular diseases. Cathepsin cysteine proteases have a central role in ECM …

The vessel wall is composed of distinct cellular layers, yet communication among individual
cells within and between layers results in a dynamic and versatile structure. The …

Abdominal aortic aneurysm (AAA) rupture is the 13th commonest cause of death in the
Western World. Although considerable research has been applied to the aetiology and …

Rationale: Matrix metalloproteinase (MMP)-28 regulates the inflammatory and extracellular
matrix responses in cardiac aging, but the roles of MMP-28 after myocardial infarction (MI) …

Inflammation and fibrosis play an important role in the development and progression of
cardiovascular diseases. Acute coronary syndrome (ACS) is caused by rupture of inflamed …

Abdominal aortic aneurysm: novel mechanisms and therapies : Current Opinion in
Cardiology Abdominal aortic aneurysm: novel mechanisms and therapies : Current Opinion …

Rupture of abdominal aortic aneurysm (AAA) represents a significant clinical event, having a
mortality rate of 90% and being currently ranked as the 13th leading cause of death in the …