Abdominal aortic aneurysms (AAA) are localized expansions of the abdominal aorta that
develop due to chronic proteolytic disruption of the structural extracellular matrix (ECM) …

Objective: Investigate the requirement of Aggrecan (Acan) cleavage during aortic wall
development in a murine model with ADAMTS (a disintegrin-like and metalloprotease …

Background: Abdominal aortic aneurysms (AAAs) are a deadly pathology with strong sexual
dimorphism. Similar to humans, female mice exhibit far lower incidences of angiotensin II …

Background and Purpose Abdominal aortic aneurysm (AAA) is a degenerative disease
affecting human health, but there are no safe and effective medications for AAA therapy …

Purpose Dabigatran etexilate (DE) constitutes a novel, direct thrombin inhibitor. Regarding
the association of thrombin with atherogenesis, we assessed the effects of DE on the …

At inflammatory sites, cytotoxic agents are released and generated from invading immune
cells and damaged tissue cells. The further fate of the inflammation highly depends on the …

AIM: This study assessed the impact of regular exercise on inflammatory markers (high-
sensitivity C-reactive protein [hsCRP], fibrinogen), and matrix metalloproteinases (MMPs) …

Abdominal aortic aneurysms (AAAs) are characterized by significant changes in the
architecture of the aortic wall, notably, loss of functional elastin and smooth muscle. Because …

Aortic aneurysms (AAs) are dilations of the aorta, that are often fatal upon rupture.
Diagnostic radiological techniques such as ultrasound (US), magnetic resonance imaging …

Abdominal aortic aneurysm (AAA) is a significant health problem in the United States, with
approximately 30,000 repair operations annually. Treatment of AAA is associated with more …