OBJECTIVE: Abdominal aortic aneurysm (AAA) is a common disease with as yet unclear
cause. Increased matrix metalloproteinase (MMP) levels in the plasma and aorta are a …

Objective—Abdominal aortic aneurysm (AAA) is a permanent dilation of the abdominal aorta
associated with rupture, which frequently results in fatal consequences. AAA tissue is …

As the most common form of aortic aneurysm, abdominal aortic aneurysm (AAA) is
associated with the proliferation and apoptosis of vascular smooth muscle cells (VSMCs) …

Ascending thoracic aortic aneurysms may be fatal upon rupture or dissection and remain a
leading cause of death in the developed world. Understanding the pathophysiology of the …

OBJECTIVE: Proinflammatory cytokines and matrix metalloproteinases (MMPs) are
prominent mediators of the connective tissue destruction that characterizes abdominal aortic …

Background: Ascending aortic aneurysms (AA) are a common, though poorly understood
medical condition. Aims: To document the histological changes in a large series of human …

OBJECTIVE: Tumor necrosis factor (TNF)-α is known to be elevated in plasma and the aorta
in abdominal aortic aneurysm (AAA) patients. We sought to clarify the role of TNF-α …

Long non-coding RNAs (lncRNAs) have been ascertained as vital modulators in abdominal
aortic aneurysm (AAA) development. In this research, the function and molecular …

Objective/Background Matrix metalloproteinases (MMPs) have already been identified as
key players in the pathogenesis of abdominal aortic aneurysm (AAA). However, the current …

BACKGROUND: The influence of intraluminal thrombus (ILT) on the proteolytic environment
within the wall of an abdominal aortic aneurysm (AAA) is unknown. This is the first study to …