[HTML][HTML] Molecular and cellular mechanisms involved in aortic wall aneurysm development

I Bararu Bojan, CE Pleșoianu, OV Badulescu… - Diagnostics, 2023 - mdpi.com
Aortic aneurysms represent a very common pathology that can affect any segment of the
aorta. These types of aneurysms can be localized on the thoracic segment or on the …

Thrombus versus wall biological activities in experimental aortic aneurysms

M Coutard, Z Touat, X Houard, A Leclercq… - Journal of vascular …, 2010 - karger.com
Background/Aim: The intraluminal thrombus (ILT) is considered to participate in abdominal
aortic aneurysm (AAA) evolution. To assess whether this role proceeds via ILT influence on …

Transforming growth factor-β and abdominal aortic aneurysms

Y Wang, S Krishna, PJ Walker, P Norman… - Cardiovascular …, 2013 - Elsevier
Abdominal aortic aneurysms (AAAs) are common problems in aged people which can be
associated with severe complications including aortic rupture and death. Transforming …

The histone methyltransferase SETDB2 modulates tissue inhibitors of metalloproteinase–matrix metalloproteinase activity during abdominal aortic aneurysm …

FM Davis, WJ Melvin, K Mangum, LC Tsoi… - Annals of …, 2023 - journals.lww.com
Objective: To determine macrophage-specific alterations in epigenetic enzyme function
contributing to the development of abdominal aortic aneurysms (AAAs). Background: AAA is …

Matrix metalloproteinases 2 and 9 in human atherosclerotic and non‐atherosclerotic cerebral aneurysms

J Caird, C Napoli, C Taggart, M Farrell… - European journal of …, 2006 - Wiley Online Library
Matrix metalloproteinases 2 and 9 (MMP 2 and‐9) have been implicated in the pathogenesis
of atherosclerosis and aneurysm formation. The goal of the study was to establish the role of …

Oral administration of diferuloylmethane (curcumin) suppresses proinflammatory cytokines and destructive connective tissue remodeling in experimental abdominal …

FE Parodi, D Mao, TL Ennis, MB Pagano… - Annals of vascular …, 2006 - Springer
Chronic transmural inflammation and proteolytic destruction of medial elastin are key
mechanisms in the development of abdominal aortic aneurysms (AAAs). Diferuloylmethane …

[HTML][HTML] Hyperlipidemia does not affect development of elastase-induced abdominal aortic aneurysm in mice

J Mulorz, JM Spin, HC Beck, MLT Thi… - Atherosclerosis, 2020 - Elsevier
Background and aims Hyperlipidemia is a suggested risk factor for abdominal aortic
aneurysm (AAA). However, whether hyperlipidemia is causally involved in AAA progression …

Differential effect of experimental hypertension and hypercholesterolemia on adventitial remodeling

J Herrmann, S Samee, A Chade… - … , and vascular biology, 2005 - Am Heart Assoc
Objective—Intima-media remodeling, as frequently assessed by changes in the external
elastic lamina-to-lumen area (EELLA), is well-described in coronary artery disease in …

Can periodontitis influence the progression of abdominal aortic aneurysm? A systematic review

L Salhi, E Rompen, N Sakalihasan, I Laleman… - …, 2019 - journals.sagepub.com
There is some evidence that periodontitis increases the risk of atherothrombosis. Abdominal
aortic aneurysm (AAA) is a cardiovascular disease with specific risk factors and …

Matrix metalloproteinase family polymorphisms and the risk of aortic aneurysmal diseases: a systematic review and meta‐analysis

T Li, Z Lv, JJ Jing, J Yang, Y Yuan - Clinical genetics, 2018 - Wiley Online Library
It has been suggested that matrix metalloproteinase (MMP) polymorphisms are associated
with the pathogenesis of aortic aneurysmal diseases. In this study, we conducted a …