[HTML][HTML] Doxycycline therapy for abdominal aortic aneurysm: inhibitory effect on matrix metalloproteinases
S Paghdar, TM Khan, NP Patel, S Chandrasekaran… - Cureus, 2021 - ncbi.nlm.nih.gov
Abdominal aortic aneurysm (AAA) is a life-threatening condition associated with smoking,
aging, atherosclerosis, and destruction of the connective tissue in the abdominal aortic wall …
aging, atherosclerosis, and destruction of the connective tissue in the abdominal aortic wall …
Expression of matrix metalloproteinases, their tissue inhibitors, and osteopontin in the wall of thoracic and abdominal aortas with dilatative pathology
V Lesauskaite, MC Epistolato, M Castagnini… - Human pathology, 2006 - Elsevier
Matrix metalloproteinases (MMPs) degrade extracellular matrix and may play a central role
in the pathogenesis of aortic aneurysms. We studied 2 groups of patients: 15 with dilatative …
in the pathogenesis of aortic aneurysms. We studied 2 groups of patients: 15 with dilatative …
Many faces of matrix metalloproteinases in aortic aneurysms
H Lu, M Aikawa - Arteriosclerosis, thrombosis, and vascular biology, 2015 - Am Heart Assoc
Lu and Aikawa MMP in Aortic Aneurysms 753 deficiency on disruption of ECM turnover
toward synthesis versus degradation (Figure). The role of MMP-2 in the synthesis of ECM is …
toward synthesis versus degradation (Figure). The role of MMP-2 in the synthesis of ECM is …
Current insights into matrix metalloproteinases and glioma progression: Transcending the degradation boundary
Glioblastoma multiforme (GBM) remains one of the most deadly cancers, with modest
advances in overall survival despite significant improvements in imaging, surgery, and …
advances in overall survival despite significant improvements in imaging, surgery, and …
Matrix metalloproteinase 2 and tissue inhibitors of metalloproteinases regulate human aortic smooth muscle cell migration during in vitro aging
As a direct correlation between aging and the risk of onset of vascular disease has been
universally accepted, we prepared an in vitro aging model consisting in sequential …
universally accepted, we prepared an in vitro aging model consisting in sequential …
Vascular tissue-type plasminogen activator promotes intracranial aneurysm formation
PE Labeyrie, R Goulay, S Martinez de Lizarrondo… - Stroke, 2017 - Am Heart Assoc
Background and Purpose—Although the mechanisms that contribute to intracranial
aneurysm (IA) formation and rupture are not totally elucidated, inflammation and matrix …
aneurysm (IA) formation and rupture are not totally elucidated, inflammation and matrix …
[HTML][HTML] Epigenetic regulation of aortic remodeling in hyperhomocysteinemia
N Narayanan, SB Pushpakumar, S Givvimani… - The FASEB …, 2014 - ncbi.nlm.nih.gov
Hyperhomocysteinemia (HHcy) is prevalent in patients with hypertension and is an
independent risk factor for aortic pathologies. HHcy is known to cause an imbalance …
independent risk factor for aortic pathologies. HHcy is known to cause an imbalance …
[HTML][HTML] Inflammation in the walls of asymptomatic abdominal aortic aneurysms is not associated with increased metabolic activity detectable by 18-fluorodeoxglucose …
G Tegler, K Ericson, J Sörensen, M Björck… - Journal of vascular …, 2012 - Elsevier
OBJECTIVE: We hypothesized that the general inflammation observed in the wall of large,
asymptomatic abdominal aortic aneurysms (AAAs) could be detected in vivo by 18 …
asymptomatic abdominal aortic aneurysms (AAAs) could be detected in vivo by 18 …
[HTML][HTML] The Relationship between the Concentration of Cathepsin A, D, and E and the Concentration of Copper and Zinc, and the Size of the Aneurysmal …
A Kurianiuk, K Socha, M Gacko… - Annals of Vascular …, 2019 - Elsevier
Background Despite advances in diagnostics and treatment, aortic aneurysms are an
important clinical problem, mainly due to the accompanying complications that may lead to …
important clinical problem, mainly due to the accompanying complications that may lead to …
[HTML][HTML] Relevance of inflammation and matrix remodeling in abdominal aortic aneurysm (AAA) and popliteal artery aneurysm (PAA) progression
M Ramella, P Bernardi, L Fusaro… - American journal of …, 2018 - ncbi.nlm.nih.gov
Aneurysm is a multifactorial degenerative disease characterized by focal dilatation of blood
vessels. Although abdominal aortic (AAA) and popliteal aneurysms (PAA) are the most …
vessels. Although abdominal aortic (AAA) and popliteal aneurysms (PAA) are the most …