Integrating scRNA-seq to explore novel macrophage infiltration-associated biomarkers for diagnosis of heart failure

S Li, T Ge, X Xu, L Xie, S Song, R Li, H Li… - BMC Cardiovascular …, 2023 - Springer
Objective Inflammation and immune cells are closely intertwined mechanisms that contribute
to the progression of heart failure (HF). Nonetheless, there is a paucity of information …

Single-cell transcriptome analysis profiling lymphatic invasion-related TME in colorectal cancer

L Wang, L Ma, Z Song, L Zhou, K Chen, X Wang… - Scientific Reports, 2024 - nature.com
Lymphatic invasion (LI) is extremely aggressive and induces worse prognosis among
patients with colorectal cancer (CRC). Thus, it is critical to characterize the cellular and …

[HTML][HTML] The heterogeneity of tumour-associated macrophages contributes to the clinical outcomes and indications for immune checkpoint blockade in colorectal …

J Tang, L Ming, F Qin, Y Qin, D Wang, L Huang, Y Cao… - Immunobiology, 2024 - Elsevier
Abstract Tumor-associated macrophages (TAMs), one of the major immune cell types in
colorectal cancer (CRC) tumor microenvironment (TME), play indispensable roles in …

[HTML][HTML] Spatial analysis of NOS2 and COX2 interaction with T-effector cells reveals immunosuppressive landscapes associated with poor outcome in ER− breast …

LA Ridnour, RYS Cheng, WF Heinz, M Pore… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Multiple immunosuppressive mechanisms exist in the tumor microenvironment that drive
poor outcomes and decrease treatment efficacy. The co-expression of NOS2 and COX2 is a …

[HTML][HTML] Resident synovial macrophages in synovial fluid: implications for immunoregulation in infectious and inflammatory arthritis

KI Cyndari, BM Scorza, ZR Zacharias, L Strand… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Objectives: Resident synovial macrophages (RSM) provide immune sequestration of the
joint space and are likely involved in initiation and perpetuation of the joint-specific immune …

[PDF][PDF] Изучение профиля моноцитов периферической крови больных колоректальным раком и здоровых доноров: магистерская диссертация по …

ИА Пацкан - 2023 - vital.lib.tsu.ru
АННОТАЦИЯ В работе был проанализирован транскрипционный профиль моноцитов
больных колоректальным раком (КРР) и здоровых доноров, а также геномный профиль …