The gasdermins, a protein family executing cell death and inflammation

P Broz, P Pelegrín, F Shao - Nature Reviews Immunology, 2020 - nature.com
The gasdermins are a family of recently identified pore-forming effector proteins that cause
membrane permeabilization and pyroptosis, a lytic pro-inflammatory type of cell death …

A guide to computational methods for G-quadruplex prediction

E Puig Lombardi, A Londoño-Vallejo - Nucleic acids research, 2020 - academic.oup.com
Guanine-rich nucleic acids can fold into the non-B DNA or RNA structures called G-
quadruplexes (G4). Recent methodological developments have allowed the characterization …

Ensembl 2020

AD Yates, P Achuthan, W Akanni, J Allen… - Nucleic acids …, 2020 - academic.oup.com
Abstract The Ensembl (https://www. ensembl. org) is a system for generating and distributing
genome annotation such as genes, variation, regulation and comparative genomics across …

Ensembl 2019

F Cunningham, P Achuthan, W Akanni… - Nucleic acids …, 2019 - academic.oup.com
Abstract The Ensembl project (https://www. ensembl. org) makes key genomic data sets
available to the entire scientific community without restrictions. Ensembl seeks to be a …

The EMBL-EBI search and sequence analysis tools APIs in 2019

F Madeira, YM Park, J Lee, N Buso, T Gur… - Nucleic acids …, 2019 - academic.oup.com
The EMBL-EBI provides free access to popular bioinformatics sequence analysis
applications as well as to a full-featured text search engine with powerful cross-referencing …

HMMER web server: 2018 update

SC Potter, A Luciani, SR Eddy, Y Park… - Nucleic acids …, 2018 - academic.oup.com
Abstract The HMMER webserver [http://www. ebi. ac. uk/Tools/hmmer] is a free-to-use
service which provides fast searches against widely used sequence databases and profile …

PlantPAN3. 0: a new and updated resource for reconstructing transcriptional regulatory networks from ChIP-seq experiments in plants

CN Chow, TY Lee, YC Hung, GZ Li… - Nucleic acids …, 2019 - academic.oup.com
Abstract The Plant Promoter Analysis Navigator (PlantPAN; http://PlantPAN. itps. ncku. edu.
tw/) is an effective resource for predicting regulatory elements and reconstructing …

PHI-base: the pathogen–host interactions database

M Urban, A Cuzick, J Seager, V Wood… - Nucleic acids …, 2020 - academic.oup.com
The pathogen–host interactions database (PHI-base) is available at www. phi-base. org. PHI-
base contains expertly curated molecular and biological information on genes proven to …

Genenames. org: the HGNC and VGNC resources in 2019

B Braschi, P Denny, K Gray, T Jones… - Nucleic acids …, 2019 - academic.oup.com
Abstract The HUGO Gene Nomenclature Committee (HGNC) based at EMBL's European
Bioinformatics Institute (EMBL-EBI) assigns unique symbols and names to human genes …

MicroScope: an integrated platform for the annotation and exploration of microbial gene functions through genomic, pangenomic and metabolic comparative analysis

D Vallenet, A Calteau, M Dubois, P Amours… - Nucleic acids …, 2020 - academic.oup.com
Large-scale genome sequencing and the increasingly massive use of high-throughput
approaches produce a vast amount of new information that completely transforms our …