The nucleus accumbens: mechanisms of addiction across drug classes reflect the importance of glutamate homeostasis

MD Scofield, JA Heinsbroek, CD Gipson… - Pharmacological …, 2016 - ASPET
The nucleus accumbens is a major input structure of the basal ganglia and integrates
information from cortical and limbic structures to mediate goal-directed behaviors. Chronic …

New developments in human neurocognition: clinical, genetic, and brain imaging correlates of impulsivity and compulsivity

NA Fineberg, SR Chamberlain, AE Goudriaan… - CNS …, 2014 - cambridge.org
Impulsivity and compulsivity represent useful conceptualizations that involve dissociable
cognitive functions, which are mediated by neuroanatomically and neurochemically distinct …

[HTML][HTML] Impulsivity, compulsivity, and top-down cognitive control

JW Dalley, BJ Everitt, TW Robbins - Neuron, 2011 - cell.com
Impulsivity is the tendency to act prematurely without foresight. Behavioral and
neurobiological analysis of this construct, with evidence from both animal and human …

Choice impulsivity: Definitions, measurement issues, and clinical implications.

KR Hamilton, MR Mitchell, VC Wing… - Personality Disorders …, 2015 - psycnet.apa.org
Impulsivity critically relates to many psychiatric disorders. Given the multifaceted construct
that impulsivity represents, defining core aspects of impulsivity is vital for the assessment …

Understanding the construct of impulsivity and its relationship to alcohol use disorders

DM Dick, G Smith, P Olausson, SH Mitchell… - Addiction …, 2010 - Wiley Online Library
There are well‐established links between impulsivity and alcohol use in humans and other
model organisms; however, the etiological nature of these associations remains unclear …

Impulsivity as a vulnerability marker for substance-use disorders: review of findings from high-risk research, problem gamblers and genetic association studies

A Verdejo-García, AJ Lawrence, L Clark - Neuroscience & Biobehavioral …, 2008 - Elsevier
There is a longstanding association between substance-use disorders (SUDs) and the
psychological construct of impulsivity. In the first section of this review, personality and …

Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates

JW Dalley, RN Cardinal, TW Robbins - Neuroscience & Biobehavioral …, 2004 - Elsevier
The prefrontal cortex has been implicated in a variety of cognitive and executive processes,
including working memory, decision-making, inhibitory response control, attentional set …

High impulsivity predicts the switch to compulsive cocaine-taking

D Belin, AC Mar, JW Dalley, TW Robbins, BJ Everitt - Science, 2008 - science.org
Both impulsivity and novelty-seeking have been suggested to be behavioral markers of the
propensity to take addictive drugs. However, their relevance for the vulnerability to …

Dissecting impulsivity and its relationships to drug addictions

JD Jentsch, JR Ashenhurst… - Annals of the New …, 2014 - Wiley Online Library
Addictions are often characterized as forms of impulsive behavior. That said, it is often noted
that impulsivity is a multidimensional construct, spanning several psychological domains …

The role of impulsive behavior in drug abuse

JL Perry, ME Carroll - Psychopharmacology, 2008 - Springer
Background Impulsivity is a multifaceted construct that has recently been recognized as a
factor contributing to enhanced vulnerability to drug abuse. Objectives In the present review …