Biomarkers and bioassays for detecting dioxin-like compounds in the marine environment
ME Hahn - Science of the Total Environment, 2002 - Elsevier
The presence of toxic chemical contaminants in some marine organisms, including those
consumed by humans, is well known. Monitoring the levels of such contaminants and their …
consumed by humans, is well known. Monitoring the levels of such contaminants and their …
Polycyclic aromatic hydrocarbons as inducers of cytochrome P4501A enzyme activity in the rainbow trout liver cell line, RTL‐W1, and in primary cultures of rainbow …
A Behrens, K Schirmer, NC Bols… - … and Chemistry: An …, 2001 - Wiley Online Library
In order to investigate cell‐specific differences in the response of in vitro models to
environmental toxicants, we compared the capacity of nine polycyclic aromatic …
environmental toxicants, we compared the capacity of nine polycyclic aromatic …
Improving human mesenchymal stem cell-derived hepatic cell energy metabolism by manipulating glucose homeostasis and glucocorticoid signaling
JS Rodrigues, A Faria-Pereira, SP Camões… - Frontiers in …, 2023 - frontiersin.org
Introduction The development of reliable hepatic in vitro models may provide insights into
disease mechanisms, linking hepatocyte dysmetabolism and related pathologies. However …
disease mechanisms, linking hepatocyte dysmetabolism and related pathologies. However …
Time-dependent transcriptional induction of CYP1A1, CYP1A2 and CYP1B1 mRNAs by H+/K+-ATPase inhibitors and other xenobiotics
S Krusekopf, I Roots, AG Hildebrandt, U Kleeberg - Xenobiotica, 2003 - Taylor & Francis
1. Xenobiotic-mediated regulation of mRNA expression of all members of the human
cytochrome P450 (CYP) 1 family has been measured by RT-PCR in the hepatoma cell line …
cytochrome P450 (CYP) 1 family has been measured by RT-PCR in the hepatoma cell line …
Toward a computational ecotoxicity assay
Thousands of anthropogenic chemicals are released into the environment each year, posing
potential hazards to human and environmental health. Toxic chemicals may cause a variety …
potential hazards to human and environmental health. Toxic chemicals may cause a variety …
From the air to the water phase: implication for toxicity testing of combustion-derived particles
S Schmidt, R Altenburger, D Kühnel - Biomass Conversion and Biorefinery, 2019 - Springer
The biological effects of airborne particulate matter (PM) in humans stimulated many
research activities in recent years. One type of particles contributing to PM are those derived …
research activities in recent years. One type of particles contributing to PM are those derived …
Joana Saraiva Rodrigues1, Andreia Faria-Pereira2, Sergio Povoas Camões1, Ana Sofia Serras1, Vanessa Alexandra Morais2, Jorge Lira Ruas3 and Joana Paiva …
JS Rodrigues - Progression to Diabetes: Molecular and Cellular …, 2023 - books.google.com
Methods: We have investigated the role of insulin, glucose and dexamethasone on
mitochondrial function, insulin signaling and carbohydrate metabolism, namely AKT …
mitochondrial function, insulin signaling and carbohydrate metabolism, namely AKT …
Cytochrome P450 (CYP1A) induction and DNA adducts in a rat hepatoma cell line (Fao), exposed to environmentally relevant concentrations of organic compounds …
L Østby, Å Krøkje - Environmental Toxicology and Pharmacology, 2002 - Elsevier
Cytochrome P4501A (CYP1A) induction and DNA adduct formation were evaluated in the
rat hepatoma cell line Fao, as biomarkers of exposure to organic compounds. Cells were …
rat hepatoma cell line Fao, as biomarkers of exposure to organic compounds. Cells were …
Application of statistical experimental design and multivariate data analysis for evaluation of mixtures using cytochrome P4501A induction
MHS Jensen, Å Krøkje - Environmental Toxicology and …, 2008 - Wiley Online Library
Abstract Cytochrome P4501A (CYP1A) induction was evaluated in the rat hepatoma cell line
H4IIE as a biomarker of exposure to organic compounds. The 3‐(4, 5‐dimethylthiazol‐2‐yl) …
H4IIE as a biomarker of exposure to organic compounds. The 3‐(4, 5‐dimethylthiazol‐2‐yl) …
Evaluation of CYP1A protein induction, biotransformation capacity and DNA adduct formation in a rat hepatoma cell line (Fao), as biomarkers of organic contamination …
Induction of cytochrome P4501A (CYP1A) immunopositive protein was evaluated in the rat
hepatoma cell line Fao, as a biomarker of organic pollution in extract of environmental soil …
hepatoma cell line Fao, as a biomarker of organic pollution in extract of environmental soil …