Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …

Sirtuins are a family of NAD+-dependent deacylases with numerous physiological and
pathological implications, which lately became an attractive therapeutic target. Sirtuin …

Selenium nanoparticles (SeNPs) are extremely popular objects in nanotechnology.“Green”
synthesis has special advantages due to the growing necessity for environmentally friendly …

Diabetic nephropathy (DN) is a renal complication of diabetic hyperglycemia. The Signal
transducer and activator of transcription 3 (Stat3) is a center molecule of the chronic …

Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by
progressive cognitive decline and the accumulation of beta-amyloid plaques and tau tangles …

Neurodegenerative disorders include different neurological conditions that affect nerve cells,
causing the progressive loss of their functions and ultimately leading to loss of mobility …

Vascular diseases, a leading cause of death in human, are strongly associated with
pathological damage to blood vessels. The selenoprotein (Sel) have been reported to play …

Both physiological and pathological aging processes induce brain alterations especially
affecting the speed of processing, working memory, conceptual reasoning and executive …

Dietary selenium (Se) intake within the physiological range is critical to maintain various
biological functions, including antioxidant defence, redox homeostasis, growth …

Alzheimer's disease (AD), the most common neurodegenerative disease, remains unclear in
terms of its underlying causative genes and effective therapeutic approaches. Meanwhile …