Stathmin (STMN) plays a vital role in maintaining the malignant behavior of cancer through
directly regulating microtubule dynamics equilibrium. Taxol, an effective chemotherapeutics …

In the pursuit of optimal anti-tumor immune effects, both “passive” and “active”
immunotherapies have made significant progress recently. In situ vaccines offer a promising …

In several solid tumors, an increased stathmin expression is associated with both poor
prognosis and resistance to certain chemotherapy types. However, the data regarding …

Low allelic and clonal variability among endogenous RNAi targets has focused mismatch
tolerance studies to RNAi-active guide strands. However, the inherent genomic instability of …

Utilization of nucleic acids to manipulate genetic information within a cell is known as gene
therapy. It has provided researchers with unprecedented opportunities in treatment and …

Prostate cancer affects 1 in 9 men in their lifetime. While disease that is detected early can
be very treatable, recurrence affects about 30% of the patients. Imaging is an important tool …

Utilization of nucleic acids to manipulate genetic information within a cell is known as gene
therapy. It has provided researchers with unprecedented opportunities in treatment and …

High-throughput sequencing of the products of 5′ RNA ligase-mediated rapid amplification
of cDNA ends (5′ RLM-RACE) reactions (RACE-SEQ) enables the mapping and digital …

Cancer nanotherapeutics comprise the main application of nanotechnology to healthcare
and are administered intravenously for faster action and maximal bioavailability. As …

The EWS/FLI1 fusion gene is well-characterized as a driver of Ewing's sarcoma. Bi-shRNA
EWS/FLI1 is a functional plasmid DNA construct that transcribes both siRNA and miRNA-like …