To identify candidate genes for intellectual disability, we performed a meta-analysis on
2,637 de novo mutations, identified from the exomes of 2,104 patient–parent trios. Statistical …

Null hypothesis significance testing (NHST) has several shortcomings that are likely
contributing factors behind the widely debated replication crisis of (cognitive) neuroscience …

Scientists often adjust their significance threshold (alpha level) during null hypothesis
significance testing in order to take into account multiple testing and multiple comparisons …

The biological interpretation of gene lists with interesting shared properties, such as up-or
down-regulation in a particular experiment, is typically accomplished using gene ontology …

We present the discovery of 25 new repeating fast radio burst (FRB) sources found among
CHIME/FRB events detected between 2019 September 30 and 2021 May 1. The sources …

Background In high-throughput studies, hundreds to millions of hypotheses are typically
tested. Statistical methods that control the false discovery rate (FDR) have emerged as …

Understanding the genetic changes underlying phenotypic variation in sheep (Ovis aries)
may facilitate our efforts towards further improvement. Here, we report the deep …

Overview: Digital transformation is reshaping entire segments and industries:
communications, retail, and, increasingly, health care, medicine, agriculture, and …

The poolr package provides an implementation of a variety of methods for pooling (ie,
combining) p values, including Fisher's method, Stouffer's method, the inverse chisquare …

Purpose To compare the diagnostic performance of radiomic analysis (RA) and a
convolutional neural network (CNN) to radiologists for classification of contrast agent …