[HTML][HTML] Activation of Nrf2/HO-1 signaling: An important molecular mechanism of herbal medicine in the treatment of atherosclerosis via the protection of vascular …

Q Zhang, J Liu, H Duan, R Li, W Peng, C Wu - Journal of advanced …, 2021 - Elsevier
Abstract Introduction Recently, Nrf2/HO-1 has received extensive attention as the main
regulatory pathway of intracellular defense against oxidative stress and is considered an …

The genus Nepeta: Traditional uses, phytochemicals and pharmacological properties

A Sharma, R Cooper, G Bhardwaj… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Nepeta is a multiregional genus of the
“Lamiaceae”(Labiatae or Mint) family. Species of Nepeta are a valuable part of traditional …

Keap1‐Nrf2 signaling pathway in angiogenesis and vascular diseases

Z Guo, Z Mo - Journal of Tissue Engineering and Regenerative …, 2020 - Wiley Online Library
The transcription factor, nuclear factor E2‐related factor 2 (Nrf2), is highly sensitive to
oxidative burst products, including reactive oxygen species (ROS) and reactive nitrogen …

Mitochondrial dysfunction and diabetic nephropathy: nontraditional therapeutic opportunities

PN Zhang, MQ Zhou, J Guo, HJ Zheng… - Journal of Diabetes …, 2021 - Wiley Online Library
Diabetic nephropathy (DN) is a progressive microvascular diabetic complication. Growing
evidence shows that persistent mitochondrial dysfunction contributes to the progression of …

[HTML][HTML] Advances in the pharmacological study of Chinese herbal medicine to alleviate diabetic nephropathy by improving mitochondrial oxidative stress

M Chen, Y Chen, W Zhu, X Yan, J Xiao, P Zhang… - Biomedicine & …, 2023 - Elsevier
Diabetic nephropathy (DN) is one of the serious complications of diabetes mellitus, primarily
arising from type 2 diabetes (T2DM), and can progress to chronic kidney disease (CKD) and …

ACE inhibitory activities of two peptides derived from Volutharpa ampullacea perryi hydrolysate and their protective effects on H2O2 induced HUVECs injury

CX Wang, CC Song, XT Liu, BW Qiao, S Song… - Food Research …, 2022 - Elsevier
The purpose of this study is to explore the effects of IVTNWDDMEK and VGPAGPRG, two
angiotensin I-converting enzyme (ACE) inhibitory peptides purified from Volutharpa …

Nepeta angustifolia CY Wu improves renal injury in HFD/STZ-induced diabetic nephropathy and inhibits oxidative stress-induced apoptosis of mesangial cells

S Huang, M Tan, F Guo, L Dong, Z Liu, R Yuan… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance As an important medicinal material constituting a variety of
traditional Chinese medicine prescriptions, Nepeta angustifolia CY Wu was used as a folk …

Phytochemical and biological investigations on two Nepeta species: Nepeta heliotropifolia and N. congesta subsp. cryptantha

M Akdeniz, A Ertas, I Yener, M Firat… - Journal of food …, 2020 - Wiley Online Library
In the present study, the essential oil and aroma compositions of Nepeta heliotropifolia (NH)
and N. congesta subsp. cryptantha (NC) were determined by gas chromatography–mass …

Mitochondrial targeting of herbal medicine in chronic kidney disease

Q Li, C Xing, Y Yuan - Frontiers in Pharmacology, 2021 - frontiersin.org
Chronic kidney disease (CKD) is a common progressive disease that is typically
characterized by the permanent loss of nephrons and an eventual decline in glomerular …

Polyphenols from Penthorum chinense Pursh. Attenuates high glucose-induced vascular inflammation through directly interacting with Keap1 protein

Y Sun, L He, W Wang, T Wang, W Hua, T Li… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Penthorum chinense Pursh is used for promoting
diuresis and alleviating “heat”-associated disorders, which were considered to be related to …