The role of microRNAs in multidrug resistance of glioblastoma
Simple Summary Glioblastoma (GBM) is one of the most malignant types of central nervous
system tumor which accounts for more than 60% of all brain tumors in adults. Owing to poor …
system tumor which accounts for more than 60% of all brain tumors in adults. Owing to poor …
miRNA-148b and its role in various cancers
N Dorraki, ZN Ghale-Noie, NS Ahmadi, V Keyvani… - …, 2021 - Taylor & Francis
miRNA-148b belongs to the family miR-148/-152, with significant differences in nonseed
sequences, which can target diverse mRNA molecules. Reportedly, it may undergo …
sequences, which can target diverse mRNA molecules. Reportedly, it may undergo …
A promising way to overcome temozolomide resistance through inhibition of protein neddylation in glioblastoma cell lines
B Brandt, M Németh, G Berta, M Szünstein… - International journal of …, 2023 - mdpi.com
There is no effective therapy for the lately increased incidence of glioblastoma multiforme
(GBM)—the most common primary brain tumor characterized by a high degree of …
(GBM)—the most common primary brain tumor characterized by a high degree of …
[HTML][HTML] MicroRNAs in adult high-grade gliomas: Mechanisms of chemotherapeutic resistance and their clinical relevance
Y Jegathesan, PP Stephen, ISEE Sati… - Biomedicine & …, 2024 - Elsevier
Notorious for its high mortality rate, the current standard treatment for high-grade gliomas
remains a challenge. This is largely due to the complex heterogeneity of the tumour coupled …
remains a challenge. This is largely due to the complex heterogeneity of the tumour coupled …
Magnetic and fluorescent dual-labeled genetically encoded targeted nanoparticles for malignant glioma cell tracking and drug delivery
AN Gabashvili, NS Chmelyuk, VV Oda, MK Leonova… - Pharmaceutics, 2023 - mdpi.com
Human glioblastoma multiforme (GBM) is a primary malignant brain tumor, a radically
incurable disease characterized by rapid growth resistance to classical therapies, with a …
incurable disease characterized by rapid growth resistance to classical therapies, with a …
Targeted glioma therapy—clinical trials and future directions
Glioblastoma multiforme (GBM) is the most common type of glioma, with a median survival of
14.6 months post-diagnosis. Understanding the molecular profile of such tumors allowed the …
14.6 months post-diagnosis. Understanding the molecular profile of such tumors allowed the …
[HTML][HTML] Transport of nanocarriers to brain for treatment of glioblastoma multiforme: Routes and challenges
S Trivedi, V Bhoyar, N Akojwar, V Belgamwar - Nano Trends, 2023 - Elsevier
Glioblastoma Multiforme (GBM) is one of the most infiltrative, heterogenous types of brain
malignancies and is mainly associated with poor prognosis. Despite various advances in …
malignancies and is mainly associated with poor prognosis. Despite various advances in …
Anticancer effect of cathelicidin LL-37, protegrin PG-1, nerve growth factor NGF, and temozolomide: impact on the mitochondrial metabolism, clonogenic potential, and …
AN Chernov, TA Filatenkova, RI Glushakov… - Molecules, 2022 - mdpi.com
Glioblastoma (GBM) is one of the most aggressive and lethal malignancy of the central
nervous system. Temozolomide is the standard of care for gliomas, frequently results in …
nervous system. Temozolomide is the standard of care for gliomas, frequently results in …
A Window of Opportunity to Overcome Therapeutic Failure in Neuro-Oncology.
MA Vogelbaum, G Li, AB Heimberger… - American Society of …, 2022 - europepmc.org
Glioblastoma is the most common primary malignant brain neoplasm and it remains one of
the most difficult-to-treat human cancers despite decades of discovery and translational and …
the most difficult-to-treat human cancers despite decades of discovery and translational and …
Metal-based nanostructured therapeutic strategies for glioblastoma treatment—an update
AM Gawel, R Singh, W Debinski - Biomedicines, 2022 - mdpi.com
Glioblastoma (GBM) is the most commonly diagnosed and most lethal primary malignant
brain tumor in adults. Standard treatments are ineffective, and despite promising results …
brain tumor in adults. Standard treatments are ineffective, and despite promising results …