T-regulatory cells (Tregs) represent a unique subpopulation of helper T-cells by maintaining
immune equilibrium using various mechanisms. The role of T-cell receptors (TCR) in …

Balanced immunity is pivotal for health and homeostasis. CD4+ helper T (Th) cells are
central to the balance between immune tolerance and immune rejection. Th cells adopt …

Multiple sclerosis (MS) is an autoimmune disease triggered by environmental factors that act
on a genetically susceptible host. It features three clinical stages: a pre-clinical stage …

In recent years, the understanding of regulatory T cell (Treg cell) biology has expanded
considerably. Key observations have challenged the traditional definition of Treg cells and …

Multiple sclerosis (MS) is a common degenerative disorder of the central nervous system.
The decreased frequency and dysfunction of Treg cells cause inflammation and disease …

In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …

Regulatory T cells (TReg cells), a specialized T cell lineage, have a pivotal function in the
control of self tolerance and inflammatory responses. Recent studies have revealed a …

THE MAMMALIAN IMMUNE SYSTEM can be broadly divided into two main arms: innate and
adaptive immunity. As its name implies, the cells and receptors of the innate immune system …

CD4+ Foxp3+ regulatory T-cells (Tregs) are a unique subset of helper T-cells, which
regulate immune response and establish peripheral tolerance. Tregs not only maintain the …

Forkhead box protein 3-expressing (FOXP3+) regulatory T cells (Treg cells) suppress
conventional T cells and are essential for immunological tolerance. FOXP3, the master …