E2F1‐mediated AUF1 upregulation promotes HCC development and enhances drug resistance via stabilization of AKR1B10

T Zhang, G Guan, J Zhang, H Zheng, D Li… - Cancer …, 2022 - Wiley Online Library
The AU‐rich binding factor 1 (AUF1) is one of the well known adenylate‐uridylate‐rich
element (ARE)‐specific RNA‐binding proteins (ARE‐BPs) for which dysregulation has been …

[HTML][HTML] Prognostic implications of preoperative, postoperative, and dynamic changes of alpha-fetoprotein and des-gamma (γ)-carboxy prothrombin expression pattern …

SC Tang, YY Wu, ZW Lin, QJ Chen, C Luo… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Background The utility of pre-and post-operative alpha-fetoprotein (AFP) and des-gamma (γ)-
carboxy prothrombin (DCP) expression patterns and their dynamic changes as predictors of …

[HTML][HTML] Fibrinogen-to-albumin ratio predicts overall survival of hepatocellular carcinoma

H Sun, J Ma, J Lu, ZH Yao, HL Ran… - World Journal of …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Fibrinogen-to-albumin ratio (FAR) has been found to be of prognostic
significance for several types of malignant tumors. However, less is known about the …

Nomograms incorporating the CNLC staging system predict the outcome of hepatocellular carcinoma after curative resection

R Liao, XF Wei, P Che, KL Yin, L Liu - Frontiers in Oncology, 2022 - frontiersin.org
Purpose Prediction models of postoperative outcomes of patients with hepatocellular
carcinoma (HCC) after surgery based on the China liver cancer (CNLC) staging system are …

Prognostic Value of Serum α‐Fetoprotein Level as an Important Characteristic of Tumor Biology for Patients Undergoing Liver Resection of Early-Stage Hepatocellular …

LQ Yao, ZQ Fan, MD Wang, YK Diao, TH Chen… - Annals of Surgical …, 2024 - Springer
Abstract Background and Objective According to the Barcelona Clinic Liver Cancer (BCLC)
algorithm, tumor burden and liver function, but not tumor biology, are the key factors in …

Short-and long-term outcomes of laparoscopic versus open liver resection for large hepatocellular carcinoma: a propensity score study

KJ Zhang, L Liang, YK Diao, YM Xie, DD Wang, FQ Xu… - Surgery today, 2023 - Springer
Purpose Laparoscopic liver resection (LLR) for hepatocellular carcinoma (HCC) remains
controversial, especially for tumors larger than 5 cm. We compared the short-and long-term …

Prognostic significance of postoperative serological incomplete conversion of AFP and PIVKA-II after hepatic resection for hepatocellular carcinoma: a multicenter …

M Wang, G Qian, H Xiao, X Liu, L Sun, Z Chen… - The …, 2024 - academic.oup.com
Background The value of serum biomarkers, particularly alpha-fetoprotein (AFP) and protein
induced by vitamin K absence or antagonist-II (PIVKA-II), gains increasing attention in …

Association between early response of alpha-fetoprotein and treatment efficacy of systemic therapy for advanced hepatocellular carcinoma: A multicenter cohort study …

G Hou, B Liu, ZQ Fan, C Li, JP Zhang, YH Guo… - Frontiers in …, 2023 - frontiersin.org
Background Alpha-fetoprotein (AFP) is a well-identified biomarker in hepatocellular
carcinoma (HCC). However, only limited AFP-related studies have evaluated its early …

Whole‐Transcriptome Sequencing Combined with High‐Dimensional Proteomic Technologies Reveals the Potential Value of miR‐135b‐5p as a Biomarker for …

Y Zhang, L He, L Pan, C Feng, X Wang… - BioMed Research …, 2023 - Wiley Online Library
Purpose. Hepatocellular carcinoma (HCC) is a disease with great heterogeneity and a high
mortality rate. It is crucial to identify reliable biomarkers for diagnosis, prognosis, and …

The combination of age, international standardized ratio, albumin and γ-glutamyl transpeptidase (AIAG), tumor size and alpha fetoprotein (AFP) stage as the …

S Liu, Z Xu, Z Fang, D Zhang, Z Qin, L Fan… - … Journal of General …, 2021 - Taylor & Francis
Background Advanced liver fibrosis can lead to cirrhosis, portal hypertension and liver
failure. Besides, advanced liver fibrosis and cirrhosis are the major risk factors for …