NADPH oxidases (NOX): an overview from discovery, molecular mechanisms to physiology and pathology

A Vermot, I Petit-Härtlein, SME Smith, F Fieschi - Antioxidants, 2021 - mdpi.com
The reactive oxygen species (ROS)-producing enzyme NADPH oxidase (NOX) was first
identified in the membrane of phagocytic cells. For many years, its only known role was in …

Intracellular delivery by membrane disruption: mechanisms, strategies, and concepts

MP Stewart, R Langer, KF Jensen - Chemical reviews, 2018 - ACS Publications
Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

Singlet oxygen, photodynamic therapy, and mechanisms of cancer cell death

PS Maharjan, HK Bhattarai - Journal of oncology, 2022 - Wiley Online Library
Photodynamic therapy (PDT) can be developed into an important arsenal against cancer; it
is a minimally invasive therapy, which is used in the treatment or/and palliation of a variety of …

Cytotoxicity of biologically synthesized silver nanoparticles in MDA‐MB‐231 human breast cancer cells

S Gurunathan, JW Han, V Eppakayala… - BioMed research …, 2013 - Wiley Online Library
Silver nanoparticles (AgNPs) have been used as an antimicrobial and disinfectant agents.
However, there is limited information about antitumor potential. Therefore, this study focused …

Green synthesis of silver nanoparticles using Ganoderma neo-japonicum Imazeki: a potential cytotoxic agent against breast cancer cells

S Gurunathan, J Raman, SNA Malek… - International journal …, 2013 - Taylor & Francis
Background Silver nanoparticles (AgNPs) are an important class of nanomaterial for a wide
range of industrial and biomedical applications. AgNPs have been used as antimicrobial …

Triggering and modulation of apoptosis by oxidative stress

J Chandra, A Samali, S Orrenius - Free radical biology and medicine, 2000 - Elsevier
Cell survival requires multiple factors, including appropriate proportions of molecular oxygen
and various antioxidants. Although most oxidative insults can be overcome by the cell's …

[HTML][HTML] Oxidative stress and diabetic retinopathy

RA Kowluru, PS Chan - Experimental diabetes research, 2007 - ncbi.nlm.nih.gov
Oxygen metabolism is essential for sustaining aerobic life, and normal cellular homeostasis
works on a fine balance between the formation and elimination of reactive oxygen species …

Glucose oxidase–polymer nanogels for synergistic cancer-starving and oxidation therapy

W Zhao, J Hu, W Gao - ACS applied materials & interfaces, 2017 - ACS Publications
Glucose oxidase (GOX) can convert glucose into gluconic acid and hydrogen peroxide
(H2O2), which is potentially useful for synergistic cancer-starving and oxidation therapy …

The green tea polyphenol (−)-epigallocatechin gallate attenuates β-amyloid-induced neurotoxicity in cultured hippocampal neurons

YT Choi, CH Jung, SR Lee, JH Bae, WK Baek, MH Suh… - Life sciences, 2001 - Elsevier
Previous evidence has indicated that the neuronal toxicity of amyloid β (βA) protein is
mediated through oxygen free radicals and can be attenuated by antioxidants and free …

[HTML][HTML] Diabetes-induced mitochondrial dysfunction in the retina

RA Kowluru, SN Abbas - Investigative ophthalmology & visual …, 2003 - tvst.arvojournals.org
purpose. Oxidative stress is increased in the retina in diabetes, and antioxidants inhibit
activation of caspase-3 and the development of retinopathy. The purpose of this study was to …