Role of LOX-1 (lectin-like oxidized low-density lipoprotein receptor 1) as a cardiovascular risk predictor: mechanistic insight and potential clinical use
J Barreto, SK Karathanasis, A Remaley… - … , and vascular biology, 2021 - Am Heart Assoc
Atherosclerosis, the underlying cause of cardiovascular disease (CVD), is a worldwide
cause of morbidity and mortality. Reducing ApoB-containing lipoproteins—chiefly, LDL (low …
cause of morbidity and mortality. Reducing ApoB-containing lipoproteins—chiefly, LDL (low …
[HTML][HTML] Oxidized LDL and NO synthesis—Biomarkers of endothelial dysfunction and ageing
D Gradinaru, C Borsa, C Ionescu, GI Prada - Mechanisms of ageing and …, 2015 - Elsevier
Oxidized LDL (oxLDL) and nitric oxide (NO) exert contradictory actions within the vascular
endothelium microenvironment influencing key events in atherogenesis. OxLDL and NO are …
endothelium microenvironment influencing key events in atherogenesis. OxLDL and NO are …
[HTML][HTML] Atherosclerotic cardiovascular disease risk assessment: An American Society for Preventive Cardiology clinical practice statement
Risk for atherosclerotic cardiovascular disease (ASCVD) shows considerable heterogeneity
both in generally healthy persons and in those with known ASCVD. The foundation of …
both in generally healthy persons and in those with known ASCVD. The foundation of …
The mannose receptor: from endocytic receptor and biomarker to regulator of (meta) inflammation
HJP van der Zande, D Nitsche, L Schlautmann… - Frontiers in …, 2021 - frontiersin.org
The mannose receptor is a member of the C-type lectin (CLEC) family, which can bind and
internalize a variety of endogenous and pathogen-associated ligands. Because of these …
internalize a variety of endogenous and pathogen-associated ligands. Because of these …
High levels of soluble lectinlike oxidized low‐density lipoprotein receptor‐1 are associated with carotid plaque inflammation and increased risk of ischemic stroke
H Markstad, A Edsfeldt, I Yao Mattison… - Journal of the …, 2019 - Am Heart Assoc
Background When the lectinlike oxidized low‐density lipoprotein (ox LDL) receptor‐1 (LOX‐
1), a scavenger receptor for ox LDL, binds ox LDL, processes leading to endothelial …
1), a scavenger receptor for ox LDL, binds ox LDL, processes leading to endothelial …
Soluble LOX‐1: a novel biomarker in patients with coronary artery disease, stroke, and acute aortic dissection?
A Hofmann, C Brunssen, S Wolk, C Reeps… - Journal of the …, 2020 - Am Heart Assoc
Cardiovascular diseases are the leading cause of death worldwide. Approximately 85% of
all deaths from cardiovascular disease are due to acute myocardial infarction (AMI) and …
all deaths from cardiovascular disease are due to acute myocardial infarction (AMI) and …
Lectin‐like oxidized low‐density lipoprotein receptor 1 inhibition in type 2 diabetes: phase 1 results
AL Vavere, M Sinsakul, EL Ongstad… - Journal of the …, 2023 - Am Heart Assoc
Background Blockade of the lectin‐like oxidized low‐density lipoprotein receptor‐1 (LOX‐1)
is a potentially attractive mechanism for lowering inflammatory and lipid risk in patients with …
is a potentially attractive mechanism for lowering inflammatory and lipid risk in patients with …
Soluble lectin‐like oxidized low density lipoprotein receptor‐1 as a biochemical marker for atherosclerosis‐related diseases
A Pirillo, AL Catapano - Disease markers, 2013 - Wiley Online Library
Lectin‐like oxidized low density lipoprotein receptor‐1 (LOX‐1), the main oxidized low‐
density lipoprotein (OxLDL) in endothelial cells, is upregulated in atherosclerotic lesions and …
density lipoprotein (OxLDL) in endothelial cells, is upregulated in atherosclerotic lesions and …
LOX-1 and atherosclerotic-related diseases
P Jin, S Cong - Clinica chimica acta, 2019 - Elsevier
Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), a scavenger receptor of
oxidized low-density lipoprotein (ox-LDL) found in various cells, plays a crucial role in the …
oxidized low-density lipoprotein (ox-LDL) found in various cells, plays a crucial role in the …
Increased levels of lectin‐like oxidized low‐density lipoprotein receptor‐1 in ischemic stroke and transient ischemic attack
T Skarpengland, M Skjelland, XY Kong… - Journal of the …, 2018 - Am Heart Assoc
Background Soluble lectin‐like oxidized low‐density lipoprotein receptor‐1 (sLOX‐1) has
been shown to be increased in patients with acute ischemic stroke. Here, we evaluated …
been shown to be increased in patients with acute ischemic stroke. Here, we evaluated …