Syndromic birth defects are rare diseases that can present with seemingly pleiotropic
comorbidities. Prime examples are rare congenital heart and cardiovascular anomalies that …

The heart is laterally asymmetric. Not only is it positioned on the left side of the body but the
organ itself is asymmetric. This patterning occurs across scales: at the organism level …

As an increasingly used alternative to perfluorooctanoic acid (PFOA), hexafluoropropylene
oxide trimer acid (HFPO-TA) has been widely detected in global water environments …

Early heart development depends on the coordinated participation of heterogeneous cell
sources. As pioneer work from Adriana C. Gittenberger-de Groot demonstrated …

During heart development, a well-characterized network of transcription factors initiates
cardiac gene expression and defines the precise timing and location of cardiac progenitor …

Developmental studies have revealed the importance of the transcription factor Hand2 in
cardiac development. Hand2 promotes cardiac progenitor differentiation and epithelial …

Objective: This research aims to increase the level and quality of the information acquired
from 90 previously conducted studies regarding zebrafish heart regeneration and to …

Most animals exhibit an external bilateral symmetry while there is an interior left-right (L/R)
asymmetry regarding the position of the visceral organs, which is fundamental for their …