The current literature on the diagnosis of periprosthetic joint infection provides controversial
evidence on the diagnostic accuracy of MLR, NLR, PVR, and PLR. Therefore, this critical …

Background To diagnose or exclude a chronic prosthetic joint infection (PJI) can be a clinical
challenge. Therefore, sensitive and specific biomarkers are needed in the diagnostic work …

Aims α-defensin is a biomarker which has been described as having a high degree of
accuracy in the diagnosis of periprosthetic joint infection (PJI). Current meta-analyses are …

George et al [1] studied 79 patients undergoing reimplantation and found that
Musculoskeletal Infection Society (MSIS) criteria had a high specificity (96%) in predicting …

Background Early detection followed by prompt intervention is essential for the treatment of
periprosthetic joint infection (PJI). D-dimer, a fibrin degradation product, characteristically …

Objective To explore the possibility of obtaining more accurate information from routine
blood tests for the diagnosis of periprosthetic joint infection (PJI). Methods This is a …

Aims Recently, several synovial biomarkers have been introduced into the algorithm for the
diagnosis of a prosthetic joint infection (PJI). Alpha defensin is a promising biomarker, with a …

Background Identifying novel biomarkers that are both specific and sensitive to
periprosthetic joint infection (PJI) has the potential to improve diagnostic accuracy and …

Prosthetic joint infection (PJI) management is not standardized worldwide and the outcome
is frequently unsatisfactory. More and more arthroplasties are now being performed. An …

Background Periprosthetic joint infection (PJI) is the most serious complication of joint
replacement surgery. Further comorbidities include bedsore, deep vein thrombosis …